Prevention of pre-eclampsia after infertility treatment: Preconceptional minimalisation of risk factors

Publication date: Available online 15 May 2019Source: Best Practice &Research Clinical Endocrinology &MetabolismAuthor(s): Hanna Hürter, Shane Vontelin van Breda, Lenka Vokalova, Marlene Brandl, Marc Baumann, Irene Hösli, Evelin Annegret Huhn, Christian De Geyter, Simona W. Rossi, Olav LapaireAbstractAlthough an increased risk of pre-eclampsia in pregnancies conceived after infertility treatment has been reported, it remains unknown whether preconceptional minimalisation of known risk factors would help in preventing pre-eclamsia. Obesity and preconceptional blood pressure are discussed as major risks for the development of pre-eclampsia and low doses of aspirins, folic acid, statins and metformin are discussed as potential preventive treatments to decrease the risk of pre-eclampsia. In the present review we discuss whether present-day reproductive medicine could progress towards complication-free pregnancy.
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research

Related Links:

Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
ConclusionLateral open wedge distal femur osteotomy combine with MPFL and MCL reconstruction and tibial tuberosity medialization realignment procedure can be successfully done for improve irreducible patellar dislocation in valgus knee, from clinical and radiological evaluation have good outcome after surgery.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
AbstractPurpose of ReviewThe benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. With the advent of non-statin medications, particularly PCSK-9 inhibitors, which can lower LDL-C to very low levels not seen before, it is important to answer some important questions regarding LDL-C lowering and the uses of these medications in clinical practice: how low should we go with LDL-C reduction? Is there a threshold beyond which lowe...
Source: Current Cardiovascular Risk Reports - Category: Cardiology Source Type: research
Acta Pharmacologica Sinica, Published online: 18 June 2019; doi:10.1038/s41401-019-0257-1Huperzine A ameliorates obesity-related cognitive performance impairments involving neuronal insulin signaling pathway in mice
Source: Acta Pharmacologica Sinica - Category: Drugs & Pharmacology Authors: Source Type: research
Confusion over cholesterol issues is everywhere and shared by most people, including doctors. Unfortunately, it means that, by seeing your primary care doctor or even cardiologist, you are being advised with information that is superficial and largely ineffective while ignoring the MANY issues that really should be addressed to manage risk for cardiovascular disease. Admittedly, these are somewhat complicated issues and even I have been guilty at times of giving overlysimplistic answers. I’ll try to keep this as straightforward as possible, but it is a bit hairy. I blame this situation on the statin drug industry, as...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Cholesterol undoctored wheat belly Source Type: blogs
(CNN) — Your social media could reveal a lot more about you than you think. Say, for example, whether you have a medical condition. In a new study, researchers were able to predict 21 types of medical conditions — ranging from pregnancy to skin disorders — by analyzing people’s Facebook profiles. Facebook status updates were “particularly effective at predicting diabetes and mental health conditions including anxiety, depression and psychoses,” the study found. The study will be published June 19 in PLOS One, a peer-reviewed open access scientific journal published since 2006 “Peop...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Offbeat CNN Facebook Source Type: news
ConclusionExperimental validation of network analysis revealed anti-diabetic effects of the plant product SGD, manifested most notably by improved serum profiles and diminished insulin resistance. These experimental results may have clinical implications.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Predicting lifespan isn’t an exact science. U.S. life expectancy is currently estimated at 78.6 years, but that one number doesn’t tell the whole story. Genes, gender, lifestyle and luck all play an important part, but it’s impossible to know exactly how much and in what proportion each ingredient influences a person’s longevity. The single best predictor, though, might not be one of these factors at all. A growing body of evidence suggests it may be a person’s zip code that holds the most information about how long they’ll live. Researchers from the New York University School of Medicin...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized data visualization public health Source Type: news
Abstract We hypothesize that, ancestrally, sex-specific immune modulation evolved to facilitate survival of the pregnant person in the presence of an invasive placenta and an immunologically challenging pregnancy - an idea we term the 'pregnancy compensation hypothesis' (PCH). Further, we propose that sex differences in immune function are mediated, at least in part, by the evolution of gene content and dosage on the sex chromosomes, and are regulated by reproductive hormones. Finally, we propose that changes in reproductive ecology in industrialized environments exacerbate these evolved sex differences, resulting...
Source: Trends in Genetics : TIG - Category: Genetics & Stem Cells Authors: Tags: Trends Genet Source Type: research
Invitae’s latest acquisition is set to firmly entrench the genetics company in the non-invasive prenatal screening (NIPS). The San Francisco-based company said it signed a definitive agreement to acquire Singular Bio for $55 million. Singular Bio specializes in developing single molecule detection technology that enables lower costs and expanded use of high-quality, cell-free, nucleic acid analysis, initially for application in NIPS. The acquisition is expected to close in the coming weeks, subject to customary closing conditions. Invitae noted the transaction will be cash neutral at close and has already...
Source: MDDI - Category: Medical Devices Authors: Tags: IVD Source Type: news
More News: Cholesterol | Eating Disorders & Weight Management | Endocrinology | Folic Acid | Fortamet | Infertility | Metformin | Obesity | Pre-eclampsia | Pregnancy | Reproduction Medicine | Statin Therapy | Vitamin B9