Herpes simplex virus of the nose masquerading as invasive fungal sinusitis: A pediatric case series

Publication date: Available online 14 May 2019Source: American Journal of OtolaryngologyAuthor(s): Neha A. Patel, Rachel Kessel, Gerald ZahtzAbstractThe management of invasive fungal sinusitis differs greatly from the management of herpes simplex virus (HSV) of the nose in immunocompromised patients. However, the diagnosis may be uncertain and a delay in treatment can lead to mortality. Here we describe the successful medical management of a series of immunocompromised pediatric patients with HSV lesions of the nose with the initial concern for invasive fungal sinusitis. The diagnosis of HSV herpes was supported by positive polymerase chain reaction (PCR) testing of the nasal lesion. To our knowledge, these are the first cases described in the pediatric literature, emphasizing the need to include this entity on the differential.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research