High frequency repetitive transcranial magnetic stimulation improves neuronal activity without affecting astrocytes and microglia density.

In conclusion, we can assume that three days of high-frequency rTMS applied in healthy rats does not alter astroglia reactivity or inflammatory responses, such as microglia proliferation. Because we have shown an upregulation of neuronal metabolic activity in many limbic brain structures, in addition to higher c-Fos levels in the nearest cortical area to the rTMS, our work provides novel insight into the effectiveness and safety of rTMS as a brain modulation therapy.
PMID: 31082456 [PubMed - as supplied by publisher]

Source: Brain Research Bulletin - May 9, 2019 Category: Neurology Authors: Candela Z, Higarza SG, Marta M, Martínez JA, Pernía AM, Arias JL Tags: Brain Res Bull Source Type: research