A comparison of intravenous sugammadex and neostigmine & #43; atropine reversal on time to consciousness during wake-up tests in spinal surgery

Conclusion: Using IV sugammadex 2 mg.kg−1 reversal provides faster responses to verbal commands than neostigmine–atropine combination during the intraoperative wake-up test in patients undergoing spinal surgery because the time to consciousness was significantly shorter. This difference was thought to be related with faster return of neuromuscular transmission because the TOF ratio was >0.9 well before return of consciousness in both groups.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research