Prognostic implications and interaction of L1 methylation and p53 expression statuses in advanced gastric cancer

TP53 is frequently mutated across various tissue types of cancers. In normal cells, long interspersed nuclear element-1 (LINE-1, L1) is mostly repressed by DNA methylation in its 5 ′ untranslated region but is act...

Source: Clinical Epigenetics - May 14, 2019 Category: Research Authors: Yun-Joo Shin, Younghoon Kim, Xianyu Wen, Nam-Yun Cho, Sun Lee, Woo Ho Kim and Gyeong Hoon Kang Tags: Research Source Type: research