Chronic Herpes Simplex Virus Infection in an Immunosuppressed Girl
A 6-year-old girl had a 3-year history of systemic juvenile idiopathic arthritis that was treated with prednisone and methotrexate. She presented with painful blisters, erosions, ulcerations with surface exudation, and crusts around mouth, oral mucosa, tongue, umbilicus, and right index finger (Figure); these had been present for 40 days. Tzanck smear revealed mutinucleated giant cells. Skin biopsy taken from umbilicus revealed numerous multinucleate giant cells and ballooning degeneration of keratinocytes.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Yue-Tong Qian, Jin-Yuan Ma, Jia-Wei Liu, Wei Liu, Dong-Lai Ma Tags: Rediscovering the Physical Exam Source Type: research
More News: Arthritis | Cold Sores | Girls | Herpes | Methotrexate | Papanicolaou (Pap) Smear | Pediatrics | Prednisone | Rheumatology | Skin | Skin Biopsy