Differential miRNAs Profile and Bioinformatics Analyses in Bone Marrow Mesenchymal Stem Cells from Adolescent Idiopathic Scoliosis Patients

Coexistence of abnormal skeletal growth and reduced bone mineral density in the context of adolescent idiopathic scoliosis (AIS) suggests disturbed bone metabolism existing in such patients. Our previous study suggested increased proliferation ability and decreased osteogenic differentiation ability of Bone marrow mesenchymal stem cells (BM-MSCs) of AIS.

Source: The Spine Journal - May 13, 2019 Category: Orthopaedics Authors: Shangyi Hui, Yang Yang, Jing Li, Na Li, Pengchao Xu, Hongling Li, Yan bin Zhang, Shengru Wang, Guanfeng Lin, Shugang Li, Guixing Qiu, Robert Chunhua Zhao, Jianguo Zhang, Qianyu Zhuang Tags: Basic Science Source Type: research