SMC accepts ceftaroline fosamil (ZinforoT) for restricted use for adults with complicated skin and soft tissue infections

Source: Scottish Medicines Consortium (SMC) Area: Evidence > Drug Specific Reviews The Scottish Medicines Consortium has accepted ceftaroline fosamil (ZinforoT) for restricted use within NHS Scotland in adults with complicated skin and soft tissue infections.   The SMC restriction applies to use in patients with known or suspected meticillin resistant Staphylococcus aureus (MRSA) infection in the following settings:   . For Gram-positive only infections where vancomycin IV is inappropriate/has not been tolerated or treatment modification is required; and daptomycin IV or linezolid IV is normally used.   . For polymicrobial Gram-positive and common Gram-negative pathogens*, where vancomycin IV in combination with gentamicin IV is inappropriate/has not been tolerated or treatment modification is required; and daptomycin IV in combination with gentamicin IV, or linezolid iv in combination with gentamicin IV, or tigecycline IV is normally used.   The SMC notes that ceftaroline should be used only on the advice of ...
Source: NeLM - Drug Specific Reviews - Category: Drugs & Pharmacology Source Type: news