Impact of Pulmonary Artery to Aorta Ratio by CT on the Clinical Outcome in Heart Failure

Pulmonary hypertension (PH) is a life-threatening condition and generally confers a poor prognosis. Among the various etiologies, left heart disease is the most common cause of the development of PH.1 The presence of PH in heart failure (HF) is associated with more severe symptom and worse exercise tolerance.2 PH also has negative impact on the clinical outcome both in HF with preserved ejection fraction (HFpEF)3 and reduced ejection fraction (HFrEF).4 Since the definite diagnosis of PH, defined as mean pulmonary artery pressure (mPAP) more than 25 mmHg, requires right heart catheterization, non-invasive methods such as tricuspid regurgitation peak gradient (TRPG) assessed by echocardiography are often used to predict PH.

Source: Journal of Cardiac Failure - May 13, 2019 Category: Cardiology Authors: Hirotaka Ieki, Yuji Nagatomo, Mayuko Tsugu, Keitaro Mahara, Nobuo Iguchi, Mitsuaki Isobe, Tsutomu Yoshikawa Source Type: research