Acute Onset of Nausea and Vomiting, Diffuse Abdominal Pain, and Profound Metabolic Acidosis 3 Years After Total Gastrectomy

A 64-YEAR-OLD, 70-kg, 170-cm man presented to the emergency department of the authors ’ institution with acute onset of nausea, vomiting, and diffuse abdominal pain. The patient denied fever, chills, weight loss, heartburn, dysphagia, hematemesis, melena, hematochezia, constipation, abdominal distention, and urinary symptoms. He stated that he had been well until the morning of adm ission. The patient's medical history was notable for gastric cancer that was initially treated with neoadjuvant chemotherapy (consisting of folinic acid, 5-fluorouracil, and oxaliplatin) and radiation therapy (total of 45 Gy in divided doses) followed by a total gastrectomy with Roux-en-Y reconstru ction 3 years before the current admission.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Diagnostic Dilemma Source Type: research

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Publication date: May 2020Source: Clinica Chimica Acta, Volume 504Author(s): Damian Jacenik, Jakub FichnaAbstractChemerin is a multifunctional protein involved among others in adipogenesis, angiogenesis and lipid as well as glucose metabolism. Chemerin is an essential factor in promotion of chemotaxis of numerous immune cell types and plays an important role in several pathophysiologic conditions. Chemerin receptors are present on monocytes/macrophages, T cells, natural killer and dendritic cells as well as neutrophils. However, the role of chemerin and chemerin receptors in immune response and gastrointestinal diseases is...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Publication date: Available online 16 February 2020Source: The Annals of Thoracic SurgeryAuthor(s): Chadrick E. Denlinger, Barry C. Gibney
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionUA leads to disruption of Rac1 and Pak1 activity with subsequent actin depolymerization and migration. Thus, use of dietary UA in cancer prevention or as adjuvant therapy is promising.
Source: Molecular Nutrition and Food Research - Category: Food Science Authors: Tags: Research Article Source Type: research
Publication date: Available online 16 February 2020Source: Biosensors and BioelectronicsAuthor(s): Khalil K. Hussain, N.G. Gurudatt, Mahmood H. Akthar, Kyeong-Deok Seo, Deog-Su Park, Yoon-Bo ShimAbstractA robust amperometric sensor was developed for the lactate detection in the extracellular matrix of cancer cells. The sensor was fabricated by separately immobilizing nicotinamide adenine dinucleotide (NAD+) onto a carboxylic acid group and lactate dehydrogenase (LDH) onto an amine group of bi-functionalized conducting polymer (poly 3-(((2,2':5′,2″-terthiophen)-3′-yl)-5-aminobenzoic acid (pTTABA)) composit...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 17 February 2020Source: Journal of Molecular BiologyAuthor(s): Jens Danielsson, Jeffrey Kenneth Noel, Jennifer Michelle Simien, Brendan Michael Duggan, Mikael Oliveberg, José Nelson Onuchic, Patricia Ann Jennings, Ellinor HaglundAbstractLeptin is an important signaling hormone, mostly known for its role in energy expenditure and satiety. Furthermore, leptin plays a major role in other proteinopathies such as cancer, marked hyperphagia, impaired immune function, and inflammation. Despite its biological relevance in human health, there are no NMR resonance assignments of the human pr...
Source: Journal of Molecular Biology - Category: Molecular Biology Source Type: research
Publication date: Available online 17 February 2020Source: Life SciencesAuthor(s): Luiz Antonio Lupi, Maira Smaniotto Cucielo, Henrique Spaulonci Silveira, Letícia Barbosa Gaiotte, Roberta Carvalho Cesário, Fábio Rodrigues Ferreira Seiva, Luiz Gustavo de Almeida ChuffaAbstractToll-like receptors (TLRs) are critical sensors related to inflammation and tumorigenesis. Among all subtypes, the TLR4 is a highly described transmembrane protein involved in the inflammatory process. The TLR4/myeloid differentiation factor 88 (MyD88) signaling pathway has been implicated in oncogenic events in several tissues an...
Source: Life Sciences - Category: Biology Source Type: research
New J. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0NJ00240B, PaperXiuhui Yin, Xianglong Li, chunling zhu, Xucong Lin, Zenghong Xie Nanotheranostic agents with integration of diagnostic and therapeutic components into one single ultrasmall nanoparticle hold great promise in cancer imaging and therapy, but still remain challenging. Here, Ag2Se@BSA-RGD quantum dots... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
CONCLUSIONS Sevoflurane-based anesthesia did not increase the incidence of POCD compared to propofol-based anesthesia at 7 days or 3 months post-operation or impact short-term post-operative prognosis. PMID: 32060257 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Conclusion: there is evidence that both carboplatin and especially cisplatin from the first doses may impair the hearing of children and adolescents, mainly affecting the cochlear function, thus, the importance of long-term audiological monitoring.RESUMO Objetivo: identificar e analisar os efeitos da quimioterapia no sistema auditivo de crian ças e/ou adolescentes com câncer tratados com cisplatina e carboplatina, avaliados por meio de procedimentos audiológicos padronizados. Métodos: buscou-se por estudos nos idiomas português brasileiro e inglês, disponíveis nas bases de dado...
Source: Revista CEFAC - Category: Speech-Language Pathology Source Type: research
ABSTRACT Objectiv:e to analyze the relationship of anxiety and depression in the preoperative period with the presence of pain in the postoperative period. Method: cohort study conducted at a university hospital in the state of Minas Gerais (Brazil), between february and July 2017, with 65 patients. A collection instrument was elaborated for the demographic and clinical characteristics. The Hospital Anxiety and Depression Scale was used to assess anxiety and depression; pain intensity was measured using the Verbal Numerical Scale. Data were submitted to descriptive and inferential statistical analysis. Results: according t...
Source: Texto e Contexto - Enfermagem - Category: International Medicine & Public Health Source Type: research
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