Topical corticosteroid irrigations in chronic rhinosinusitis

ConclusionMany factors are associated with efficacious and adequate treatment of primary CRS. The pathology must be correctly diagnosed and be inflammatory in nature. The treatment paradigm should include wide and complete endoscopic sinus surgery for the adequate delivery of topical therapy. Topical therapy should be delivered in large ‐volume, low‐pressure devices with adequate dosing. Although there is some systemic absorption, multiple studies have demonstrated that long‐term, daily use of topical corticosteroids does not increase intraocular pressure, suppress the hypothalamic‐pituitary‐adrenal axis, or increase the risk of subcapsular cataracts. Therefore, topical corticosteroid irrigations should be considered a part of first‐line medical treatment in postsurgical CRS patients.
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: REVIEW ARTICLE Source Type: research

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Abstract Autoimmune polyendocrine syndrome type 1 (APS1) is a scarce polyendocrinopathy with autosomal recessive inheritance results from defects in the human autoimmune regulatory (AIRE) gene. In addition to three major manifestations of APS1 including mucocutaneous candidiasis, hypoparathyroidism, and Addison's disease, ophthalmic problems such as keratoconjunctivitis, dry eye, iridocyclitis, and cataract can be seen in these patients. In this article, we introduced two siblings presented with nail dystrophia, severe photophobia, and keratitis since early childhood which genetic examination revealed single nucle...
Source: Iranian Journal of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Iran J Allergy Asthma Immunol Source Type: research
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Source: Protein and Peptide Letters - Category: Biochemistry Authors: Tags: Protein Pept Lett Source Type: research
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Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: P457 Source Type: research
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Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Paediatric Asthma and Allergy Source Type: research
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Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
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Source: Health Care Renewal - Category: Health Management Tags: Becker ' s Hospital Review EPIC healthcare IT dissatisfaction JAMIA Max Green Source Type: blogs
Ben shared his 3-week experience living the Wheat Belly lifestyle after being diagnosed with celiac disease: “My family doctor diagnosed me with celiac and wheat allergies. These pictures were taken 3 weeks apart: prior to the diagnosis and three weeks later, a photo of me after following the Wheat Belly books that my doctor recommended I get. “I still feel like I eat like a king. I am just a lot more cautious about what I put into my body and I am seeing the results!” You can see that Ben’s face shows the changes we expect to see as inflammation recedes: reduced cheek and around-the-eyes edema, la...
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