The Impact of Gender on Oncologic Outcomes of Bladder Cancer The Impact of Gender on Oncologic Outcomes of Bladder Cancer

How do bladder cancer outcomes differ between males and females?Current Opinion in Urology
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Urology Journal Article Source Type: news

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Discussion MDSCs violently emerge in pathological conditions in an attempt to limit potentially harmful immune and inflammatory responses. Mechanisms supporting their expansion and survival are deeply investigated in cancer, in the perspective to reactivate specific antitumor responses and prevent their contribution to disease evolution. These findings will likely contribute to improve the targeting of MDSCs in anticancer immunotherapies, either alone or in combination with immune checkpoint inhibitors. New evidence indicates that the expansion of myeloid cell differentiation in pathology is subject to fine-tuning, as its...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
In conclusion, osmotic burst of inflated complement-damaged cells may occur, but these bursts are most likely a consequence of metabolic collapse of the cell rather than the cause of cell death. The Complement Cell Death Mediator: A Concerted Action of Toxic Moieties Membrane pores caused by complement were first visualized by electron microscopy on red blood cell membranes as large ring structures (22). Similar lesions were viewed on E. coli cell walls (23). Over the years, ample information on the fine ultrastructure of the MAC that can activate cell death has been gathered (24) and has been recently further examined (...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
CONCLUSIONS: QHT has proven to be a safe alternative for the treatment of intermediate and high risk NMIBC, with AE mainly grade 1-2. The AEs reported have little variation with respect to the dose of MMC used, presenting different "profiles" related to the device used for its administration. The treatments with QHTMMC are well tolerated, without adding significantly more AE than the instillations of MMC alone and presenting a better toxicity profile than those reflected in the literature with respect to the treatment with BCG. PMID: 29745932 [PubMed - in process]
Source: Archivos Espanoles de Urologia - Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research
When I was in South Africa last year, I met a revolutionary winemaker… His wine was completely organic. It had no toxins, and it contained powerful antioxidant properties. It was infused with a local herb called rooibos, also known as “red bush.” You may have seen rooibos tea on supermarket shelves. I immediately knew this wine should be made widely available in America — and I’m still hopeful a distributor will bring it here. I enjoy a nice glass of red wine from time to time, but the trouble with most of the wines sold in America is that they’re loaded with dangerous chemicals. Winema...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Health additives natural organic Sulfites wine Source Type: news
Britain's healthcare cost-effectiveness agency NICE, which decides if medicines should be used on the state health service, has decided Roche's immunotherapy drug Tecentriq is worth using to treat certain patients with bladder cancer.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news
Conclusions: Peroral arsenic has little effect on local airway immune responses to bacteria but compromises respiratory epithelial barrier integrity, increasing systemic translocation of inhaled pathogens and small molecules. https://doi.org/10.1289/EHP1878 Received: 09 March 2017 Revised: 14 August 2017 Accepted: 16 August 2017 Published: 28 September 2017 Address correspondence to M.B. Fessler, National Institute of Environmental Health Sciences, 111 T.W. Alexander Dr., P.O. Box 12233, Maildrop D2-01, Research Triangle Park, NC 27709 USA. Telephone: (919) 541-3701. Email: fesslerm@niehs.nih.gov *Current address: UN...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusions: Nature contact may offer a range of human health benefits. Although much evidence is already available, much remains unknown. A robust research effort, guided by a focus on key unanswered questions, has the potential to yield high-impact, consequential public health insights. https://doi.org/10.1289/EHP1663 Received: 26 January 2017 Revised: 12 May 2017 Accepted: 25 May 2017 Published: 31 July 2017 Address correspondence to H. Frumkin, Dept. of Environmental and Occupational Health Sciences, University of Washington School of Public Health, Box 354695, Seattle, WA 98195-4695 USA; Telephone: 206-897-1723;...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
Having a dog offers companionship, gives you an excuse to exercise, brings you happiness and provides entertainment. But did you know that owning a dog can also have potential health benefits, both mentally and physically, for you and your family? There is scientific evidence that touts some of the health perks of owning a pup. Take a look at how these six ways having a dog could be good for your health. 1. Stay active Dogs need to be exercised. They can’t be cooped up all day without having the chance to get up and run around. Having a dog encourages owners to take them for walks, play fetch, and get moving. And we...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
A 77-year-old neurologically intact woman presented in hypertensive crisis (blood pressure [BP] 220/110 mm Hg) resulting in pulmonary edema. The patient had a history of remote (over 40 years) repaired aortic coarctation, breast cancer in remission, hypertension managed with 6 antihypertensive medications, and allergy to iodinated contrast. Her BP was reduced to as low as 134/26 mm Hg. Subsequently she developed acute paraplegia. Examination revealed nonlocalizing lower back and abdominal pain. Tibial pulses were absent, but extremities remained warm to touch. On neurologic examination, the abnormal findings were present o...
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: CT, MRI, All Clinical Neurology, Spinal cord infarction Case Source Type: research
1. Improve heart health Dogs don’t just fill your heart; they actually make it stronger. Studies show that having a canine companion is linked to lower blood pressure, reduced cholesterol, and decreased triglyceride levels, which contribute to better overall cardiovascular health and fewer heart attacks. What’s more, dog owners who do have heart attacks have better survival rates following the events. 2. Keep you fit and active Health experts recommend that adults get about 2 hours and 30 minutes worth of moderate exercise per week. Dog owners are way more likely to hit that goal. “People love to be outs...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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