But Maybe Autism Parents Can Let Go?
What’s the other side of the “I can never die?” plaint of the autism parent? I’ve done a lot of writing about the need for more protections of our vulnerable guys who do not live with us. Even so, for many of us that is not a sustainable solution. And we are not the center of the issue, even though we love our children and want to protect them. No, they themselves are. And it is their right as human beings to claim their independence if that is what they wish. So — perhaps we parents can take a lesson from — of all things — the story of Abraham and Isaac. Not the sacrifice part — sacrificing your child is never the right thing to do — but more metaphorically, in the sense that author Jon Levenson may have meant, in The Death and Resurrection of the Beloved Son — that our children are actually not really our own, our possessions. They are born to us to protect, teach, and love, but the purpose of having children is to create beautiful souls who can live lives of meaning and goodness. So when a very good friend of mine who had read Levenson’s book raised the possibility that the Isaac story in terms of the very real necessity of letting your child go, it made me think, and it gave me comfort. “We do what we can to keep them safe,” my friend said, “but ultimately what happens to them is not up to us.” She’s not a Fatalist or a religious extremist. She believes in free will. But ...
CONCLUSION: These findings indicate increased resistance of E. coli to ciprofloxacin in comparison with prior studies. Further research in this field will increase our knowledge and more effective exposure to the antibiotic resistance of the pathogenic microorganisms. PMID: 31198116 [PubMed - as supplied by publisher]
CONCLUSIONS: During antihypertensive treatment, several dermatological reactions may occur. Clinicians should inform their patients of the increased risk of cutaneous lesions associated with the use of these drugs, and perform periodic examination of the skin. PMID: 31195782 [PubMed - as supplied by publisher]
In this study, MCF-7 and T47D cells were treated with inhibitors of 17β-HSD1, 17β-HSD7, aromatase or steroid sulfatase (STS), then mRNA levels of 17β-HSD7, STS, 11β-HSD 2, estrogen receptors α (ERα) and androgen receptor (AR) were determined by Q-PCR. ER negative cell line MDA-MB-231 was used as a negative control. Our results demonstrate that 17β-HSD7, STS and 11β-HSD2 are all regulated by the same estrogen estradiol via ERα. When the gene of ERα (ESR1) was knocked down, there was no longer significant mutual regulation of these enzymes.Our results demonstrate that imp...
This study demonstrated promising anticancer and antibacterial effects of Artemia salina egg extracts. Our results suggest that pure bioactive compounds obtained from Artemia salina eggs can provide new insights into the mechanisms of colon and skin cancer, as well as Pseudomonas aeruginosa inhibition. PMID: 31198432 [PubMed]
ConclusionBy utilizing ABC, hospital managers have a valuable accounting system that provides a true insight into the organizational costs of their department. The results of this study indicated that there are differences between the real price of radiology services and approved tariffs. Suggest until tariff amending, hospital commence to modify financial and personnel structures and repair its costs.
Abstract Trophinin-associated protein (TROAP) is a cytoplasmic protein required for microtubular cytoskeleton regulation and spindle assembly, and its expression plays a critical role in the initiation and progression of various types of cancer. However, little is known about the role of TROAP in breast cancer (BC). TROAP mRNA expression levels and clinical data from Gene Expression Omnibus (GEO) datasets (GSE42568, 104 BC patients; GSE1456, 159 BC patients; and GSE21653, 266 BC patients) were analyzed by the R2: Genomics Analysis and Visualization Platform to estimate overall survival (OS). We also analyzed the g...
ConclusionsStress conditions induced by locoregional therapies stimulated hCSC enrichment and proliferation, which could be suppressed by niclosamide and inhibitors of pathways important for hCSC renewal. Future studies will determine whether combining locoregional therapies with adjuvant hCSC inhibitors reduces HCC recurrence.
ConclusionTOL methodology allowed effective training of both groups of readers. The iterative nature of individual training ensured production of user-friendly materials including frequently-asked-questions sheets. It allowed for each person to feel that their views were fully listened to and incorporated into the training package, allowing for training materials with high face validity.
In this study, predictors of LOS were identified using a survival model that considered age as a continuous variable, separate comorbidities, and the discharge destination. Our findings are consistent with earlier reports and confirm the strong associations linking LOS to diabetes, day of surgery, and discharge destination in France. We also identified predictors of discharge to rehabilitation and of readmission within 30 days.Level of evidenceIV, retrospective observational cohort study.
Publication date: Available online 14 June 2019Source: Orthopaedics &Traumatology: Surgery &ResearchAuthor(s): D. Saragaglia, B. Rubens-Duval, R. PailhéAbstractExtra- and intra-articular proximal tibia malunion is not uncommon. Functional impact is variable but may lead to almost total impotence. The present study aimed to provide a review on malunion, answering 5 questions: (1) How should malunion be classified, and with what pathogenicity? Malunion results from reduction defect and/or secondary displacement in tibial plateau fracture (A2, A3, B, C on the AO classification), but also from previous epiphysio...
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