Targeting RIPK1 for the treatment of human diseases [Cell Biology]

RIPK1 kinase has emerged as a promising therapeutic target for the treatment of a wide range of human neurodegenerative, autoimmune, and inflammatory diseases. This was supported by extensive studies which demonstrated that RIPK1 is a key mediator of apoptotic and necrotic cell death as well as inflammatory pathways. Furthermore, human...

http://www.pnas.org/content/116/20/9714.short?rss=1

Source: Proceedings of the National Academy of Sciences - May 13, 2019 Category: Science Authors: Alexei Degterev, Dimitry Ofengeim, Junying Yuan Tags: Inaugural Articles Biological Sciences Source Type: research