An Option to Consider for Alternating Hemiplegia of Childhood: Aripiprazole

We report the medical treatment in a case of AHC in a-12-year-old male patient with convulsions. The patient did not respond to available therapies for AHC, except for aripiprazole. After the initiation of aripiprazole therapy, duration and frequency of hemiplegia episodes were decreased. Also, he is currently seizure-free with topiramate treatment for 3 months. On follow-up, a compound heterozygous ATP1A3 mutation c.868C> T (p.R290C)/c.684 + 1G> A was determined. Aripiprazole may reduce the attacks of AHC, which are resistant to other available therapies.
Source: Clinical Neuropharmacology - Category: Neurology Tags: Case Reports Source Type: research