Total clavicle reconstruction with free peroneal graft for the surgical management of chronic nonbacterial osteomyelitis of the clavicle: a case report

Chronic nonbacterial osteomyelitis (CNO) is a rare chronic autoinflammatory syndrome affecting mainly children and young adults. The natural history of the disease is marked by recurrent pain as the mainstay o...
Source: BMC Musculoskeletal Disorders - Category: Orthopaedics Authors: Tags: Case report Source Type: research

Related Links:

Conclusions: Although the mFI correlated with 30-day mortality in univariate analysis, it was not a significant predictor in multivariate analysis. An increase in age and the number of levels involved elevated the 1-year mortality risk. PMID: 30866620 [PubMed - as supplied by publisher]
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
CONCLUSIONSSeveral risk factors lead to failure of antibiotics and progression of disease in patients with ESRD. Challenges to diagnosis include vague presenting symptoms, co-existing destructive spondyloarthropathy, poor immune response, chronic elevations of inflammatory markers, and recurrent bacteremia. Infectious processes are more likely to cause permanent neurological deficits than transient deficits. The authors recommend close observation and serial imaging of these patients for early signs of neurological deficits. Any signs of disease progression will require aggressive surgical debridement. PMID: 30771765 ...
Source: Journal of Neurosurgery.Spine - Category: Neurosurgery Authors: Tags: J Neurosurg Spine Source Type: research
ConclusionPotential sequela of osteomyelitis is ankylosis of affected joints. In this particular case, imaging provides evidence of regional ankylosis of the cervical spine. Considering the patient did not complain of cervical pain or related symptoms apart from lack of cervical range of motion, and his Neck Disability Index score was 2 out of 50 (4%), no intervention was provided to the cervical spine. The patient reported he self-managed well, worked full-time as a postal worker after he was discharged due to the injury to his neck, and planned to retire in less than one month at age 70. The patient demonstrates successf...
Source: Chiropractic and Manual Therapies - Category: Complementary Medicine Source Type: research
Discussion. Patients with HGPS frequently suffer from acute and chronic pain because of musculoskeletal abnormalities and unintentional injuries. These injuries occur because of bone deformities, malfunctioning joints, and gait problems.2 Opioid pain medications are frequently used to treat acute pain conditions and for palliative care management in these cases.4 Clinicians should be aware that, because of accelerated aging, individuals with HGPS differ in their response to specific opioid analgesics. The metabolism and the rate of elimination of opioids from the body could vary significantly in these patients. They might ...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Letters to the Editor Pain pain management Source Type: research
Conclusions The recent advancement of knowledge and management strategies of SSc-SU achieved during the last years lead to the clear-cut improvement of patients' quality of life and reduced long-term disability.
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Rationale: Sclerosing osteomyelitis of Garré is a rare condition that occurs most commonly in tubular bones and the mandible. Its nontypical symptoms, low morbidity, and insidious process make its diagnosis difficult at an early stage. In this article, we reported a case of chronic sclerosing osteomyelitis which occurred in flat bone. Patient concerns: A 53-year-old man was diagnosed with rib sclerosing osteomyelitis of Garré who had an 8-year course of intermittent local pain and swelling, which radiated toward the left side of his chest wall. Chest computed tomography (CT) showed irregular sclerosis of...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Conclusions: Immunocompromised patients should be identified prior to treatment, and the small possibility of devastating complications should be thoughtfully weighed against the potential benefit of the procedure. Conservative management should be maximized initially, and if a procedure is done, strict asepsis must be maintained. Prophylaxis for S. aureus should be considered for immunocompromised patients undergoing interventional spine procedures.
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: Chronic and Interventional Pain: Case Report Source Type: research
ConclusionThe wounds of most BU patients attending the primary health care level can be adequately managed. Additionally, the patients are closer to their families and means of livelihood. Non-healing wounds can be predicted by wound area reduction between 2 to 4 weeks after initiation of treatment. Patients with clinically BU suspicious, but PCR negative ulcers need to be followed up to capture missed diagnoses.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Girl, nine years old, referred with history of right parotid swelling for a year, diagnosed with mumps. After two months, she was hospitalized for suspicion of cytomegaloviruses. Clinical status regressed and reoccurred after a month. She was unsuccessfully treated with antibiotics and had monthly episodes of severe pain. Extraoral examination showed a slight increased volume in the right face, firm consistency and painful on touch. Intraoral examination showed intact mucosa, normal color, slight expansion of the right mandibular ramus and lockjaw.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Tags: Poster presentation Source Type: research
ConclusionNon‐bacterial osteomyelitis may coexist with other autoinflammatory diseases. MRI remains a favorable diagnostic tool and genetic testing may have a limited role in selected cases. Infliximab and canakinumab are associated with variable outcomes, and 6‐week or less dosing intervals for both medications may be more effective.
Source: APLAR Journal of Rheumatology - Category: Rheumatology Authors: Tags: Original Article Source Type: research
More News: Children | Chronic Pain | Orthopaedics | Osteomyelitis | Pain | Pain Management