Assessment of the accuracy of truebeam intrafraction motion review (IMR) system for prostate treatment guidance

AbstractIntrafraction motion review (IMR), a real-time 2D, motion management feature of the Varian Truebeam ™ incorporates triggered imaging, automatic fiducial marker detection and automatic beam hold. With the increasing adoption of high dose per fraction stereotactic body radiotherapy (SBRT) this system provides a potential means to ensure treatment accuracy. The goal of this study was therefore to i nvestigate and quantify key performance characteristics of IMR for prostate treatment guidance. Phantom experiments were performed with a custom Computerized Imaging Reference Systems, Inc (CIRS) pelvis phantom with implanted gold seeds and the Hexamotion™ 5D motion platform. The system accuracy w as assessed statically and under typical prostate motion trajectories. The IMR functionality and marker detectability was tested under different anatomical conditions and with different imaging acquisition modes. Imaging dose for triggered imaging modes was determined using an ionisation chamber bas ed on IPEMB dose calibration protocol for kV energies. For zero displacement, the IMR demonstrated submillimeter agreement with the known position. Similarly, dynamic motion differences between the IMR reported position and 2D trajectory displacement were within 1 mm. Static displacement in the ant erior direction was reported by IMR as sinusoidal motion on the x-axis (kV angle). The 2D nature of IMR limits the ability to detect motion out of the plane of the kV image detector. Using...
Source: Australasian Physical and Engineering Sciences in Medicine - Category: Biomedical Engineering Source Type: research