Functional transepithelial transport measurements to detect nephrotoxicity in vitro using the RPTEC/TERT1 cell line.

In conclusion, these data demonstrate that functional parameters are important, highly sensitive and meaningful additional readouts for nephrotoxicity assessment in human renal proximal tubule epithelial cells.
PMID: 31076804 [PubMed - as supplied by publisher]

Source: Archives of Toxicology - May 9, 2019 Category: Toxicology Authors: Secker PF, Schlichenmaier N, Beilmann M, Deschl U, Dietrich DR Tags: Arch Toxicol Source Type: research