First use of an organobismuth reagent in C(sp3)–S bond formation: Access to aryl cyclopropyl sulfides via copper-catalyzed S–Cyclopropylation of thiophenols using tricyclopropylbismuth

Publication date: 15 August 2019Source: Journal of Organometallic Chemistry, Volume 893Author(s): Emeline Benoit, Bianca Bueno, Catherine Choinière, Alexandre GagnonAbstractThe direct S-cyclopropylation of thiophenols using tricyclopropylbismuth is reported. The reaction is catalyzed by copper(II) acetate and operates under mild conditions to afford the corresponding aryl cyclopropyl sulfides in moderate to good yields. This reaction represents the first use of an organobismuth reagent in C(sp3)–S bond formation.Graphical abstract

Source: Journal of Organometallic Chemistry - May 13, 2019 Category: Chemistry Source Type: research