Angiotensin II Type 1 Receptor Blocker, Fimasartan, Reduces Vascular Smooth Muscle Cell Senescence by Inhibiting the CYR61 Signaling Pathway.

CONCLUSIONS: Ang II induced vascular senescence by the ERK/p38 MAPK-CYR61 pathway and ARB, fimasartan, protected against Ang II-induced vascular senescence. PMID: 31074217 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31074217?dopt=Abstract

Source: Korean Circulation Journal - May 12, 2019 Category: Cardiology Tags: Korean Circ J Source Type: research

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