Suicidality and risk of suicidality in psoriasis: A critical appraisal of two systematic reviews and meta-analyses.

CONCLUSION: Singh et al. concluded that patients with psoriasis have a significantly higher risk of suicidal ideation, suicide attempts, and completed suicides, while Chi et al concluded that the available limited, very low-quality evidence does not support the notion of an association between psoriasis on the one hand, and suicide, suicidal ideation and attempts on the other. This article is protected by copyright. All rights reserved. PMID: 31074832 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research

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CONCLUSION: Psychiatric and physical disorders carried greatly increased risks and numbers of suicides in South Korea. Schizophrenia was the strongest risk factor, especially 35-65 years, and depression was the most common in suicide victims among ICD-10 disorders in South Korea. PMID: 31042694 [PubMed]
Source: Psychiatry Investigation - Category: Psychiatry Tags: Psychiatry Investig Source Type: research
To the Editor: Significantly increased risks for depression and suicidality have been found in psoriasis patients,1 and psoriasis has been independently associated with major depression.2 Therefore, it is important to be able to identify depression and suicidal ideation and behavior (SIB) among psoriasis patients. Standardized screening tools, such as the Patient Health Questionnaire-2 (PHQ-2), enable rapid identification of depression and SIB within minutes, making screening feasible, efficient, and effective in the outpatient setting.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Tags: Research letter Source Type: research
This study examined the risks of a range of adverse events in a large cohort of patients prescribed long‐term opioids using the UK Clinical Practice Research Datalink.MethodsPatients with musculoskeletal conditions starting a new long ‐term opioid episode (defined as ≥3 opioid prescriptions within 90 days) between 2002‐2012 were included. Primary outcomes: major trauma and intentional overdose (any). Secondary outcomes: addiction (any), falls, accidental poisoning, attempted suicide/self‐harm, gastrointestinal pathology a nd bleeding, and iron deficiency anaemia. ‘Control’ outcomes (unrelated to opio...
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: Original Article Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Researchers from the Hôpitaux de Paris in France have read Nabokov's letters to his wife, Vera, in which he details the intense frustration of living with the common skin condition.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
It’s peculiar but instructive: phenomena triggered by re-exposure after being confidently wheat- and grain-free. The re-exposure can be intentional, as in “Just one can’t hurt!” or it can be inadvertent, as in “That gravy looks safe.” Typically, someone will be wheat/grain-free for at least a week. Re-exposure from, say, salad dressing or seasoning mix then triggers re-exposure fireworks. The most common re-exposure phenomena to are: Gastrointestinal distress, bloating, and diarrhea that can last hours to a couple of days. (People with celiac disease can have problems for months, h...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates Detox Gliadin grain-free grains Inflammation joint pain re-exposure wheat belly Source Type: blogs
Psoriasis is a chronic systemic inflammatory skin disease, which has been associated with an increased risk of numerous medical and psychiatric comorbidities, including suicidality. Suicidality, which can be divided into the categories of suicidal ideation...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
Authors: Hashim PW, Chen T, Lebwohl MG, Marangell LB, Kircik LH Abstract Brodalumab, a fully human antibody of the interleukin-17 receptor, is highly effective in the treatment of moderate-to-severe plaque psoriasis. However, based on safety signals identified in clinical trials, brodalumab carries a boxed warning regarding possible risks of suicidal ideation and behavior (SIB). The validity of this link remains controversial, especially in the context of the psoriasis population as well as clinical trial data from other recently approved treatments. Herein, we critically examine the association between brodalumab ...
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Authors: Wu KK, Armstrong AW Abstract Psoriasis is a chronic inflammatory skin disease with under-investigated and underappreciated links to psychiatric comorbidities, including anxiety, depression, and suicidality. In this review, we synthesize and discuss the literature investigating the association between psoriasis and three measures of suicidality: suicidal ideation, suicide attempts, and completed suicide. Studies have shown that psoriasis is significantly linked to all three measures of suicidality, but the available data on suicide attempts and completed suicides is limited and less consistent. Studied risk...
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
Psoriasis is a chronic inflammatory skin disease with under-investigated and underappreciated links to psychiatric comorbidities, including anxiety, depression, and suicidality. In this review, we synthesize and discuss the literature investigating the ass...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
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