Monocytes Inadequately Fill In for Meningeal Macrophages.

Monocytes Inadequately Fill In for Meningeal Macrophages.
Trends Immunol. 2019 May 06;:
Authors: Song E, Iwasaki A
Abstract
In the meninges, a unique subset of tissue-resident macrophages serves as a sentinel population against invading microorganisms while suppressing harmful inflammation. A recent report shows that when murine meningeal macrophages are killed by viruses, circulating monocytes repopulate the open niche. However, they fail to mimic all aspects of tissue-resident macrophages.
PMID: 31072686 [PubMed - as supplied by publisher]

Source: Trends in Immunology - May 5, 2019 Category: Allergy & Immunology Authors: Song E, Iwasaki A Tags: Trends Immunol Source Type: research