SMRT: The 'tunnel game' helps prep kids for MRI scans

MONTREAL - Developing alternatives to using anesthesia during pediatric MRI...Read more on AuntMinnie.comRelated Reading: Pediatric patients go to the dogs for MRI anxiety relief Can Legos make MRI scans less scary for patients? A SMART way to reduce pediatric sedation MRI delays Pediatric patients use app to prep for MRI scan Pediatric-friendly MRI can enhance sedation
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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ConclusionA mock scanner was an efficient tool to improve efficiency of the explanation and to decrease anxiety in children and motion artifacts in pediatric MRI.
Source: Pediatric Radiology - Category: Radiology Source Type: research
Conclusions: Both 2-[18F]A85380 and [18F]Nifene were successfully employed in PET/CT mouse brain imaging for the kinetic study of α4β2Rs nicotine receptor, making this study the first to use 2-[18F]A85380 in mouse models. The selectivity of the synthesized probes is consistent with other publications showing the distribution of the α4β2 nicotine receptor in the brain of human and mice. With an understanding of the differences in probe kinetics, we will be able to better study the precise mechanism of nicotine receptor upregulation and the displaceable binding of nicotine and varenicline, which has imp...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Basic Science (Neurosciences) Posters Source Type: research
For the 16 years that Dr. Brian Westerberg, a Canadian surgeon, worked volunteer missions at the Mulago National Referral Hospital in Kampala, Uganda, scarcity was the norm. The patients usually exceeded the 1,500 allotted beds. Running water was once cut off when the debt-ridden hospital was unable to pay its bills. On some of his early trips, Westerberg even brought over drugs from Canada in order to treat patients. But as low-cost generics made in India and China became widely available through Uganda’s government and international aid agencies in the early 2000s, it seemed at first like the supply issue had been ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized generic drugs medication medicine Source Type: news
This study was designed to evaluate the effectiveness of a non-pharmacological intervention to reduce anxiety in pediatric patients preparing for MRI using animal-assisted therapy.Materials and methodsAn animal intervention pilot study was performed in patients who agreed in advance to interact with a dog. Patients and caregivers filled out questionnaires, including questions designed to capture changes in patient emotion before and after the intervention. MRI diagnostic quality was compared to age- and gender-matched control groups with and without general anesthesia.ResultsThe intervention in 21 patients comparing pre- a...
Source: Pediatric Radiology - Category: Radiology Source Type: research
Conclusions: In vivo exposure to remifentanil exerts a beneficial effect against excitotoxicity on the developing mouse brain, which is associated with a reduction in the size of ibotenate-induced brain lesion as well as prevention of some behavioral deficits in young mice. The long-term effect of neonatal exposure to remifentanil should be investigated. Introduction The potential neurotoxicity of anesthetics in the perinatal period prompted the US Food and Drug Administration (FDA) to release a drug safety communication warning in 2016 that stated, “repeated or lengthy use of general anesthetics or sedation ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Joong-Goo Kim1,2, Han-Bin Lee2 and Sang-Beom Jeon2* 1Department of Neurology, Jeju National University Hospital, Jeju, South Korea 2Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea Objectives: The use of dexmedetomidine and ketamine (DEX–KET) combination for magnetic resonance imaging (MRI) sedation has not been evaluated. We investigated the efficacy and safety of DEX–KET for sedation of patients undergoing MRI of the brain. Methods: This quasi-experimental study was conducted to compare the DEX–KET combination and midazolam for MRI sed...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion Currently available pharmacotherapies for PTSD are poorly effective on a substantial proportion of patients. Given this high rate of pharmacological unresponsiveness, further studies are needed to extend the knowledge of the basic mechanisms associated with the pathophysiology of this disorder. The findings discussed in this review suggest that DAergic dysfunction, especially genetic-dependent DAergic alteration, plays a prominent role in the pathophysiology of PTSD; as a consequence, drugs targeting the DAergic system might be therapeutically relevant. A better understanding of how and which DAergic dysfunctio...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Nicola Cellini1,2, Renee E. Shimizu3, Patrick M. Connolly3, Diana M. Armstrong4, Lexus T. Hernandez2, Anthony G. Polakiewicz3, Rolando Estrada3†, Mario Aguilar-Simon3, Michael P. Weisend4†, Sara C. Mednick2 and Stephen B. Simons3* 1Department of General Psychology, University of Padova, Padova, Italy 2Department of Cognitive Science, University of California, Irvine, Irvine, CA, United States 3Teledyne Scientific &Imaging, Durham, NC, United States 4Rio Grande Neurosciences, Dayton, OH, United States Transcranial electrical stimulation (tES) during sleep has been shown to successfully modula...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
Conclusion: XYS may have the ability of resistance to stress, enhancement immunity and promotion nerve cell regeneration by regulating the expression of multiple genes in numerous pathways and repaired the stress-induced impairments in hippocampal structure and function by inducing cytoskeletal reorganization. These results may provide the possible target spots in the treatment of stress in rats with XYS. Introduction Xiaoyaosan (XYS) which was first recorded in the Prescriptions of the Bureau of Taiping People's Welfare Pharmacy contains Radix Bupleuri, Rhizoma Atractylodis Macrocephalae, Radix Paeoniae Al...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
In this study, we compared the dynamic resting-state local and large-scale FC between PTSD patients (n = 22) and healthy controls (HC; n = 22; conducted as standard deviation in resting-state local and large-scale FC over a series of sliding windows). Local dynamic FC was examined by calculating the dynamic regional homogeneity (dReHo), and large-scale dynamic FC (dFC) was investigated between regions with significant dReHo group differences. For the PTSD patients, we also investigated the relationship between symptom severity and dFC/dReHo. Our results showed that PTSD patients were characterized by I) increased dynamic (...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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