Proteomic Studies of putative molecular signatures for Biological Effects by Korean Red Ginseng

ConclusionThe DEPs appear to increase the innate and acquired immunity as well as immune cell movement. These results suggest that KRG can stimulate immune responses. This analysis refined our targets of interest to include the potential functions of KRG. Furthermore, we validated the potential molecular targets of the functions, representatively LCN2, CRAMP, and HLA-DQB1 by western blotting. These results may provide molecular signature candidates to elucidate the mechanisms of the immune response by KRG. Here, we demonstrate a strategy of tissue proteomics for the discovery of the molecular function of KRG.Graphical abstract
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research