Yet Another Significant Acquisition in the Orthopedics Market

Tis the season for M&A in the orthopedics market. This time out Medtronic is acquiring Titan Spine for an undisclosed sum. Mequon, WI-based Titan Spine markets a full line of Endoskeleton interbody devices featuring its textured surface in the U.S., Europe, and Australia through its sales force and a network of independent distributors. Dublin-based Medtronic said interbody implants are spacers that can be inserted between the vertebrae during spinal fusion surgery to help relieve pressure on nerves and hold the vertebrae in place while fusion occurs. Implant material and shape is thought to play a role in the bone growth process during fusions, and today there is a growing demand from surgeons for titanium interbody devices. "We've built the broadest Spine portfolio - implants, instruments, enabling technologies, and biologics - in order to provide complete procedural solutions for surgeons' biggest challenges," Jacob Paul, senior vice president and president of the Spine division, which is part of the Restorative Therapies Group at Medtronic, said in a release. "Titan Spine has pioneered the spine implant surface technology category over the past several years. We feel that surface-enhanced titanium implants combined with our comprehensive biologics portfolio can have a positive impact on patient outcomes in spinal procedures."  Medtronic said the deal is set to close during its first fiscal quarter ending July 26, subject to the ...
Source: MDDI - Category: Medical Devices Authors: Tags: Orthopedics Source Type: news

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g Liu The accurate segmentation of the paraspinal muscle in Magnetic Resonance (MR) images is a critical step in the automated analysis of lumbar diseases such as chronic low back pain, disc herniation and lumbar spinal stenosis. However, the automatic segmentation of multifidus and erector spinae has not yet been achieved due to three unusual challenges: (1) the muscle boundary is unclear; (2) the gray histogram distribution of the target overlaps with the background; (3) the intra- and inter-patient shape is variable. We propose to tackle the problem of the automatic segmentation of paravertebral muscles using a defo...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
Condition:   Lumbar Spinal Stenosis Interventions:   Device: active tDCS;   Device: sham tDCS Sponsor:   Istanbul University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Boston Scientific has slowed its M&A pace considerably this year compared to 2018, but that doesn't mean the company won't take advantage of tuck-in opportunities that come its way. Case in point, the company's pending $465 million cash acquisition of Vertiflex, announced on Wednesday. Carlsbad, CA-based Vertiflex is a private company that sells the Superion Indirect Decompression System, a device designed to improve physical function and reduce pain in patients with lumbar spinal stenosis (LSS). The procedure, which is primarily performed by doctors who treat chronic pain patients with therapies including spinal cord stim...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Orthopedics Source Type: news
Lumbar spinal stenosis (LSS) is a common and often debilitating condition in older people. It is characterized by neurogenic claudication, consisting of lower limb pain and neurological symptoms exacerbated by walking [1]. Patients with LSS often avoid walking because of neurogenic claudication, and have reduced walking distance and physical activity [2,3]. Inadequate physical activity is linked to the development of many chronic diseases such as cardiovascular diseases, type 2 diabetes, neurodegenerative diseases, and certain cancers [4].
Source: The Spine Journal - Category: Orthopaedics Authors: Tags: Clinical Study Source Type: research
The aim of this observational, cross-sectional study was to analyse lumbar magnetic resonance imaging (MRI) findings in patients with non-specific chronic low back pain (CLBP), and to evaluate any correlation with pain intensity and their capacity to predict neuropathic pain (NP) in these patients. Fifty-two patients with non-specific CLBP, between 21 and 62 years of age, 50% men, were investigated. Lumbar MRI was employed to assess disc degeneration, endplate changes, Modic changes, disc displacement, facet degeneration, foraminal stenosis and central lumbar spinal stenosis. The characteristics of pain were evaluated and...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Treating chronic low back pain (CLBP) with spine-focused interventions is common, potentially dangerous, and often ineffective. We posit that CLBP in older adults is a geriatric syndrome – a final common pathway for the expression of multiple contributors. We have published evidence and expert consensus-based algorithms to guide evaluation and treatment of key biopsychosocial CLBP contributors in older adults – hip osteoarthritis, myofascial pain, fibromyalgia, sacroiliac joint syndrome, lumbar spinal stenosis, leg length inequality, lateral hip/thigh pain, anxiety, depression, insomnia, and maladaptive coping....
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Objectives: Assessment of neuropathic pain in chronic low back syndromes is important. However, there is currently no gold standard for its diagnosis. The aim of this observational cross-sectional study was to assess the neuropathic component of pain in various chronic low back pain syndromes using a range of diagnostic tests. Materials and Methods: Included in this study were 63 patients with chronic axial low back pain (ALBP), 48 patients with chronic radicular syndromes (CRS) comprising 23 with discogenic compression (CDRS) and 25 with lumbar spinal stenosis (LSS), and 74 controls. PainDETECT questionnaire (PDQ), q...
Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Original Articles Source Type: research
A previous study showed that transforaminal balloon adhesiolysis via the safe triangle was effective in lumbar spinal stenosis. However, retrodiscal pathology is difficult to treat with this method. Therefore we attempted retrodiscal balloon adhesiolysis via Kambin's triangle. The design of our study is a retrospective analysis. The setting of our study is a tertiary, interventional pain management practice, speciality referral center. The primary indication for this procedure is radicular pain arising from ipsilateral retrodiscal pathology. Medical records were reviewed of patients who received retrodiscal decompression ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
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