The Role of Neuraxial Opioids in Pediatric Practice

Neuraxial-spinal and epidural-administration of opioids can be an effective method for controlling pain for children in a number of clinical settings. Understanding the basic pharmacologic and logistical concepts will make it easier for pediatricians to advocate for their patients, and support patients and families when circumstances suggest that neuraxial opioid treatment is appropriate. This review article summarizes the basic concepts of pharmacology, drug choice, side effects, and complications as well as situations in which neuraxial opioids are appropriate in children.
Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Special Topic Series on Opioid Therapeutics and Concerns in Pediatrics Source Type: research

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ConclusionSurgical resection of the tumor may relieve the spinal cord compression in a neglected case. Even though the neurologic function after surgery rarely returns to the functional stage due to chronic neural tissue damage.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Conclusions: Stress-exaggerated visceral mechanonociception after antral cold exposure may involve up-regulation of TRPA1 expression and function on vagal afferents. Our findings reveal a novel mechanism for abnormal gastrointestinal cold sensing in IBS. PMID: 31327223 [PubMed]
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research
Condition:   Undefined Intervention:   Behavioral: Valsalva Maneuver Sponsor:   Indonesia University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Azadinia F, Ebrahimi-Takamjani I, Kamyab M, Asgari M, Parnianpour M Abstract The characteristics of postural sway were assessed in quiet standing under three different postural task conditions in 14 patients with nonspecific chronic low back pain and 12 healthy subjects using linear and nonlinear center of pressure parameters. The linear parameters consisted of area, the mean total velocity, sway amplitude, the SD of velocity, and the phase plane portrait. The nonlinear parameters included the Lyapunov exponent, sample entropy, and the correlation dimension. The results showed that the amount of postural s...
Source: Motor Control - Category: Neurology Tags: Motor Control Source Type: research
BACK pain is a simple fact of life for many people. The toils of everyday living can place stress on this important part of the body. There are a number of ways to ease the discomfort, one study suggests this popular indoor activity may help.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
SUMMARY OBJECTIVE: To investigate the efficacy and safety of percutaneous transforaminal endoscopic discectomy (PTED) in the treatment of lumbar spinal stenosis (LSS) combined with osteoporosis. METHODS: Eighty patients with LSS combined with osteoporosis were divided into a control and PTED group, which received conventional transforaminal lumbar interbody fusion and PTED, respectively. The surgical indications, incision visual analogue scale (VAS), lumbar and leg pain VAS, lumbar Japanese Orthopaedic Association (JOA) and Oswestry disability index (ODI) scores, bone mineral density (BMD), and adverse reactions were obser...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
CONCLUSION This case demonstrates that, similarly to Graves ’ disease, Hashitoxicosis can also be triggered by stressful life events.RESUMO OBJETIVO Mesmo que o estresse seja conhecido h á muito tempo como um fator provocativo para a doença de Graves, sua relação com a tireoidite de Hashimoto é mais controversa. Estudos sobre esse tema são escassos. O objetivo deste artigo é relatar um caso de Hashitoxicose induzida por estresse. RESULTADOS Aqui nós relatamos um caso de Has hitoxicose induzido por um evento psicológico estressante em uma mulher de 28 anos...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
SUMMARY OBJECTIVE: To investigate clinical curative effects of lumbar oblique-pulling manipulation in combination with sling-exercise-therapy training on chronic nonspecific lower back pain. METHODS: A total of 60 patients with chronic nonspecific lower back pain in the Outpatient Department were included in this study. These patients were randomly divided into two groups: the observation group and the control group. The control group adopted a single sling-exercise-therapy training three times a week, while the observation group adopted lumbar oblique-pulling manipulation in combination with manipulation treatment once a ...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
A recent study from the U.S. showed that the technique, which uses radio-frequency waves, is 90 per cent effective, reports the European Spine Journal
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Conclusions: The MIS-OLIF technique at the L2–L5 levels has shown encouraging early surgical outcomes with a good fusion rate and rapid recovery. While utilizing the unfamiliar oblique trajectory, the use of navigation can guide the surgeon in real time and also help in reducing the radiation exposure.
Source: Neurology India - Category: Neurology Authors: Source Type: research
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