Cleaners vote overwhelmingly for strike action to halt privatisation at the Princess Alexandra

Cleaners at the Princess Alexandra Hospital in Harlow have today (Friday) voted almost unanimously in favour of strike action against plans to outsource cleaning services. UNISON members voted 99% in favour of industrial action on an 84% turnout. The 220 staff that provide cleaning and domestic services warn that if jobs are transferred to the private sector it could spell disaster for patients. Research has shown that hospitals with outsourced cleaning have higher rates of infection than those with in-house services. The cleaners warn that pay and conditions will fall below NHS colleagues if services are outsourced, as a private company would not be part of any future NHS pay awards. And new starters could also face worse employment terms, with a private contractor having no obligation to pay more than the legal minimum. UNISON has recently won NHS pay rates for health workers employed by private companies in Doncaster, Liverpool, and Bolton. However, it is far better for staff and for patients if services aren’t outsourced in the first place, says UNISON. Employees will now discuss their next steps, including possible strike dates. UNISON has urged the Princess Alexandra Hospital to abandon its privatisation plans to avoid industrial action. UNISON general secretary Dave Prentis said: “All too often the reality of outsourcing is lower pay, a longer working day and reduced job security after a private firm takes over. Service users rarely see any benefit, it...
Source: UNISON Health care news - Category: UK Health Authors: Tags: News Press release dave prentis NHS nhs pay outsourcing strike Source Type: news

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Background: In US cystic fibrosis (CF) patients, methicillin-resistant Staphylococcus aureus (MRSA) rates have tripled in the past 2 decades. Known clinical risk factors include exposure to a healthcare setting, Pseudomonas aeruginosa and CF-related diabetes. Area-level socio-environmental exposures have not been evaluated. We explored the association of area-level deprivation with MRSA prevalence in a pediatric CF Center in the Southeastern United States. Methods: Patients’ residential addresses were geocoded and linked to a composite Area Deprivation Index and Rural-Urban Commuting Area scores. The association...
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
Publication date: December 2019Source: Phytochemistry Letters, Volume 34Author(s): Shi-Ting Wang, Wen-Qi Qian, Peng He, Mei-Qing Feng, Yun Kang, Ya-Qin Wang, Jian-Ming HuangAbstractTwo new glycoalkaloids, manshurienine C (1) and 8-oxotetrahy-corydalmine-1-O-β-D-glucopyranoside (2), along with eleven known alkaloids (3–13), were isolated from the tubers of Stephania succifera. Their structures were elucidated by spectroscopic methods, including NMR and MS spectra. Compounds 5, 6, 8, and 10 showed in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).Graphical abstract
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
Conclusions: Oridonin antibacterial mechanism was related to changes in cell membrane and cell wall permeability, disturbance in protein and DNA metabolism, and influence on bacterial morphology. Thus, oridonin may help in treating MRSA infection. PMID: 31622118 [PubMed - in process]
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
On 3 October 2019,  Lynette Martell MRPharmS, aged 65 years of Warrington, Cheshire. Mrs Martell registered with the Society in 2000. 
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Authors: Bassetti M, Carnelutti A, Castaldo N, Peghin M Abstract Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) infections represent a leading cause of infection-related morbidity and mortality worldwide. There has been a welcome increase in the number of agents available for the treatment of MRSA infection over the last decade and several clinical trials are currently investigating the role of new experimental strategies. Areas covered: The purpose of this manuscript is to review the efficacy and safety of recently approved anti-MRSA molecules as well as some newer agents currently under investig...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Authors: Yu H, Wang Y, Wang X, Guo J, Wang H, Zhang H, Du F Abstract Bacterial resistance to antimicrobial agents, including multidrug resistance, is an increasing problem in the treatment of infectious diseases. The development of resistance-modifying agents represents a potential strategy to alleviate the spread of bacterial resistance to antibiotics. A checkerboard microdilution assay was used to determine the synergy of jatrorrhizine and the antibiotic, norfloxacin (NFX). A bacterial ethidium bromide efflux assay, reverse transcription semi-quantitative polymerase chain reaction analysis and molecular docking s...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Publication date: January 2020Source: Materials Science and Engineering: C, Volume 106Author(s): Ling-Yuan Guo, Shu-Zhen Yan, Xin Tao, Qing Yang, Qiang Li, Tian-Shu Wang, Shu-Qin Yu, Shuang-Lin ChenAbstractThere is an urgent need for new antibacterial strategies to overcome the emergence of antibiotic resistance. Antibacterial photodynamic therapy (APDT) may be an effective method to deliver photosensitizers for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. Here, we report that the photosensitizer hypocrellin A (HA) loaded into lipase-sensitive methoxy poly (ethylene glycol)-block-poly(&ep...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
In this study, we show that the Staphylococcus aureus COL (MRSA) strain, with a known complete genome, can easily survive and grow under acidic and alkaline conditions (pH5 and pH9, respectively), both planktonically and as a biofilm. A microarray-based analysis of both planktonic and biofilm cells was performed under acidic and alkaline conditions showing that several genes are up- or down-regulated under different environmental conditions and growth modes. These genes were coding for transcription regulators, ion transporters, cell wall biosynthetic enzymes, autolytic enzymes, adhesion proteins and antibiotic resistance ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Staphylococcus epidermidis is an opportunistic human pathogen, which is involved in numerous nosocomial and implant associated infections. Biofilm formation is one of the prime virulence factors of S. epidermidis that supports its colonization on biotic and abiotic surfaces. The global dissemination of three lineages of S. epidermidis superbugs highlights its clinical significance and the imperative need to combat its pathogenicity. Thus, in the current study, the antibiofilm activity of umbelliferone (UMB), a natural product of the coumarin family, was assessed against methicillin-resistant S. epidermidis (MRSE). UMB exhi...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Publication date: Available online 16 October 2019Source: Journal of Microbiological MethodsAuthor(s): Deepshikha Bhowmik, Bhaskar Jyoti Das, Piyush Pandey, Shiela Chetri, Debadatta Dhar Chanda, Amitabha BhattacharjeeAbstractStaphylococcal Cassette Chromosome mec (SCCmec) element plays a key role in development of resistance by carrying different resistance factors. Therefore, routine and rapid diagnostic approach is considered advantageous for the easy detection of SCCmec elements. So, here we have described the use of three sets of multiplex PCR assay, which can be used to identify SCCmec type I to type XII, unlike other...
Source: Journal of Microbiological Methods - Category: Microbiology Source Type: research
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