Analysis of host cell binding specificity mediated by the Tp0136 adhesin of the syphilis agent Treponema pallidum subsp. pallidum

ConclusionsOur results show that Tp0136 facilitates differential level of binding to cell lines representing various host tissues, which highlights the importance of this protein in colonization of human organs byT.pallidum and resulting syphilis pathogenesis.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research

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Preliminary Proposal Deadline Date: June 24, 2019 Program Guidelines: NSF 19-517The Materials Research Science and Engineering Centers (MRSECs) program provides sustained support of interdisciplinary materials research and education of the highest quality while addressing fundamental problems in science and engineering. Each MRSEC addresses research of a scope and complexity requiring the scale, synergy, and multidisciplinarity provided by a campus-based research center. The MRSECs support materials research infrastructure in the United States, promote active ...More at https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=5295...
Source: NSF Upcoming Due Dates - Category: Science Source Type: funding
LYME disease is a relatively unknown condition with an estimated 2,000 to 3,000 new cases each year in England and Wales. For an unknown disease however, anyone can develop the condition as its caught by a tick. This major symptom could mean you might have Lyme disease. Do you have it?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 24 May 2019Source: Molecular Phylogenetics and EvolutionAuthor(s): Giuliana Allegrucci, Valerio SbordoniAbstractWe investigated the molecular phylogenetic divergence and historical biogeography of cave crickets belonging to the family Rhaphidophoridae (Orthoptera, Ensifera). We used taxa representative of most of the regions embraced by the family, considering samples of Macropathinae from Gondwana land (i.e., Tasmania, Australia, New Zealand, South Africa, and South America); Aemodogryllinae and Rhaphidophorinae from Southern-eastern Asia (i.e., India, Bhutan, China, Philippines and the ...
Source: Molecular Phylogenetics and Evolution - Category: Molecular Biology Source Type: research
No abstract available
Source: AJN - Category: Nursing Tags: In the News Source Type: research
The U.S. diagnostic market celebrated three regulatory firsts last week.  1. FDA Authorizes Marketing of First Zika Test Until now, tests for detecting Zika virus immunoglobulin (IgM) antibodies in blood were only authorized for emergency use under FDA's Emergency Use Authorization (EUA) authority. On Thursday, the agency said it has authorized marketing of the ZIKV Detect 2.0 IgM Capture ELISA under the agency's traditional premarket authority. The test is manufactured by InBios International. “At the onset of the Zika virus outbreak, when little was known about the disease or how...
Source: MDDI - Category: Medical Devices Authors: Tags: Regulatory and Compliance IVD Source Type: news
California lawmakers are headed toward a confrontation with first-term Gov. Gavin Newsom over whether to continue a tax that can generate nearly $2 billion for low-income health care benefits
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Conclusions: Clinicians should be aware of measles complications and treatment. Public and private health efforts should continue to focus on immunization, given significant implications of measles infections for patients and healthcare systems. Future studies may assess complications of measles across the United States as individual outbreaks often occur in specific populations, making generalization of results challenging.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
The number of infants born with HIV in the United States has decreased for years, approaching the Centers for Disease Control and Prevention’s incidence goal for eliminating perinatal HIV transmission. We reviewed recent literature on perinatal HIV transmission in the United States. Among perinatally HIV-exposed infants (whose mothers have HIV, without regard to infants’ HIV diagnosis), prenatal and natal antiretroviral use has increased, maternal HIV infection is more frequently diagnosed before pregnancy and breast-feeding is uncommon. In contrast, mothers of infants with HIV are tested at a lower rate for HI...
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: HIV Reports Source Type: research
No abstract available
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Current Abstracts Source Type: research
(Natural News) And there it is. WikiLeaks founder Julian Assange has been charged by the Trump administration’s Justice Department with 17 counts of violating the Espionage Act, carrying a maximum sentence of 175 years in prison. Exactly as Assange and his defenders have been warning would happen for nearly a decade. (Article by Caitlin Johnstone republished...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
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