Medical News Today: What's the difference between Humalog and NovoLog?
Humalog and NovoLog are types of medication that can help control blood sugar levels in people with diabetes. Learn about the differences between them here.
Background: Many of those aging with HIV suffer from distal neuropathic pain (DNP) due to HIV-associated sensory neuropathy (HIV-SN). Prior studies have linked chronic pain conditions to a variant of the catechol-O-methyltransferase (COMT), Val158Met. This variant confers reduced enzymatic activity and results in higher synaptic dopamine levels. Here we examined the role of Val158Met as a predictor of DNP in HIV-SN. Methods: In 1044 HIV-infected individuals enrolled in CNS HIV Antiretroviral Therapy Effects Research, an observational study across six US institutions, we characterized the relationship between Val158Met...
Conclusion: ART-naive Ethiopian HIV patients had a high prevalence of prediabetes and diabetes, with a poor agreement between HbA1c and OGTT. Diabetes was associated with inflammation, but not with adiposity and age. Diabetes was linked to insulin deficiency, rather than insulin resistance, which may represent a different entity than type 1 and 2 diabetes. This has implications for choice of drugs, when managing diabetes in African HIV patients.
Conclusion: Neuropsychiatric illness increased odds of being frail on a predominantly physical/motoric measure, but only when symptomatic. Lack of association with asymptomatic impairment may reflect the importance of functional limitation to frailty, or possibly a unique resilience phenotype. Understanding why sex and symptomatic neuropsychiatric illness are associated with frailty will be important in managing HIV-associated morbidity in aging populations.
All about the Ambulatory Glucose Profile (AGP), that standardizes how blood sugar data is reported for doctors and patients dealing with diabetes.
I joined a group from JDRF San Diego for a great group training ride this morning to finish off my third week of training for #ScottsDeathRide (100 miles in Death Valley this October with @erikdouds for JDRF – learn more and support us at https://diabadass.com/death-valley). I finished the week with 79.08 miles in the books (plus a handful of fun basketball sessions), and I’m feeling great!Coach Pat took us on a beautiful route that I really enjoyed! I’ll definitely ride some of those roads again to take in the views. (Stick around for a bonus clip at the end to watch my wife try to kill me with the garag...
Journal of Diabetes Investigation, Volume 10, Issue 4, Page 877-878, July 2019.
AbstractPositron emission tomography/computed tomography (PET/CT) is a standard procedure for imaging cancer commonly used in the clinical practice for several diseases, in particular for cancer staging, restaging, treatment monitoring and radiation therapy planning. Despite the availability of many radiotracers, 18F-fluoro-2-deoxy-2-d-glucose ([18F]FDG) is the most used. International PET/CT guidelines propose protocols for patients ’ correct preparation before [18F]FDG injection, in particular with the regard of diabetic patients and therapy management. Hyperglycemic conditions and oral or insulin medication showed...
Conclusions/interpretationFollowing an episode of severe hypoglycaemia managed by EMS, one-fifth of participants required hospital admission, more likely in those with advancing age, increasing comorbidities and injury and one-tenth required EMS again for severe hypoglycaemia in a 3 month period, more likely in those with a greater number of antecedent episodes and lower HbA1c. Knowledge of these factors associated with admission and recurrence provides an opportunity for development of targeted strategies aimed at prevention of severe hypoglycaemia in those most vulnerable.