A new Borrelia on the block: Borrelia miyamotoi - a human health risk?

ConclusionsWith co-infection of tick-borne pathogens being commonplace, diagnostic improvements remain important. Developing in vivo models might allow more insight into human pathogenesis. Continued ecological and human case studies are key to better epidemiological understanding, guiding intervention strategies. PMID: 31064634 [PubMed - in process]
Source: Euro Surveill - Category: Infectious Diseases Authors: Tags: Euro Surveill Source Type: research

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ConclusionCustomer satisfaction with community pharmacist-administered seasonal influenza vaccinations is high in Switzerland.
Source: Journal of Pharmaceutical Policy and Practice - Category: Pharmaceuticals Source Type: research
The Maryland company, which has never brought a vaccine to market, has started its Phase 3 trial in the United Kingdom, with plans to begin in the United States in October.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Novavax Inc Clinical Trials Vaccination and Immunization Coronavirus (2019-nCoV) Johnson & Moderna Inc Pfizer Inc Research Influenza Drugs (Pharmaceuticals) Great Britain United States Source Type: news
CONCLUSIONS: YHPG has significant antiviral effects in IFV-infected mice, partially by inhibiting influenza virus replication and regulating the occurrence of apoptosis induced by influenza virus infection, suggesting that YHPG may be a promising antiviral agent with potential clinical application prospects. PMID: 32962483 [PubMed - as supplied by publisher]
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
Procalcitonin testing on admission seems to be a valuable piece of information for early risk assessment and ruling out bacterial co-infection in COVID-19 patients.
Source: SCCM PodCast - iCritical Care - Category: Intensive Care Authors: Tags: Medicine Source Type: podcasts
CONCLUSIONS: The endemic common respiratory pathogens are more prevalent than SARS-CoV-2 in the SARS-CoV-2 non-epidemic areas of this research. Detection of the pathogen is the unique means for definite COVID-19 diagnosis. PMID: 32965014 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Abstract Infectious viruses pose a threat to all living organisms, including humans, and can cause significant morbidity. Previous experience with pigs in medical education and research, rather than in domestic control settings, has led to a unique perspective on viral infections in swine. In this article, common porcine infectious diseases have been listed, based mainly on the authors' experience thus far. For example, young domestic pigs that were used in surgical training and infected with hepatitis E were subjected to quarantine and isolation treatment, and attempts were made to develop a DNA vaccine for swine...
Source: Acta Cirurgica Brasileira - Category: Surgery Authors: Tags: Acta Cir Bras Source Type: research
(American Geophysical Union) Scientists have spotted a once-in-a-century climate anomaly during World War I that likely increased mortality during the war and the influenza pandemic in the years that followed.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
(Washington University School of Medicine) Researchers have identified two antibodies that protect mice against lethal infections of influenza B virus, report scientists at Washington University School of Medicine in St. Louis and Icahn School of Medicine at Mount Sinai. Together with an antibody that targets the other major kind of influenza viruses that infect people -- influenza A -- these antibodies potentially could form the basis of a broad-spectrum flu drug that could treat almost all flu cases.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Contributor : Lisa E WagarSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTonsil organoid cultures were prepared from one donor and stimulated with live-attenuated influenza vaccine (LAIV) or left unstimulated. Cells were harvested on the days described below, total T and B cells were sorted, and cells were sequenced using the BD Rhapsody platform with a targeted set of immune-related genes, BCR, and TCR repertoire analysis.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Authors: Fattorini L, Creti R, Palma C, Pantosti A, Unit of Antibiotic Resistance and Special Pathogens, Unit of Antibiotic Resistance and Special Pathogens of the Department of Infectious Diseases, Istituto Superiore di Sanità, Rome Abstract Current literature shows that secondary bacterial infections, although less frequent than in previous influenza pandemics, affect COVID-19 patients. Mycoplasma pneumoniae, Staphylococcus aureus, Legionella pneumophila, Streptococcus pneumoniae, Haemophilus and Klebsiella spp. are the main species isolated. Of note, Mycobacterium tuberculosis-COVID-19 coinfections are al...
Source: Annali dell Istituto Superiore di Sanita - Category: General Medicine Tags: Ann Ist Super Sanita Source Type: research
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