A new Borrelia on the block: Borrelia miyamotoi - a human health risk?
ConclusionsWith co-infection of tick-borne pathogens being commonplace, diagnostic improvements remain important. Developing in vivo models might allow more insight into human pathogenesis. Continued ecological and human case studies are key to better epidemiological understanding, guiding intervention strategies. PMID: 31064634 [PubMed - in process]
ConclusionCustomer satisfaction with community pharmacist-administered seasonal influenza vaccinations is high in Switzerland.
The Maryland company, which has never brought a vaccine to market, has started its Phase 3 trial in the United Kingdom, with plans to begin in the United States in October.
CONCLUSIONS: YHPG has significant antiviral effects in IFV-infected mice, partially by inhibiting influenza virus replication and regulating the occurrence of apoptosis induced by influenza virus infection, suggesting that YHPG may be a promising antiviral agent with potential clinical application prospects. PMID: 32962483 [PubMed - as supplied by publisher]
Procalcitonin testing on admission seems to be a valuable piece of information for early risk assessment and ruling out bacterial co-infection in COVID-19 patients.
CONCLUSIONS: The endemic common respiratory pathogens are more prevalent than SARS-CoV-2 in the SARS-CoV-2 non-epidemic areas of this research. Detection of the pathogen is the unique means for definite COVID-19 diagnosis. PMID: 32965014 [PubMed - as supplied by publisher]
Abstract Infectious viruses pose a threat to all living organisms, including humans, and can cause significant morbidity. Previous experience with pigs in medical education and research, rather than in domestic control settings, has led to a unique perspective on viral infections in swine. In this article, common porcine infectious diseases have been listed, based mainly on the authors' experience thus far. For example, young domestic pigs that were used in surgical training and infected with hepatitis E were subjected to quarantine and isolation treatment, and attempts were made to develop a DNA vaccine for swine...
(American Geophysical Union) Scientists have spotted a once-in-a-century climate anomaly during World War I that likely increased mortality during the war and the influenza pandemic in the years that followed.
(Washington University School of Medicine) Researchers have identified two antibodies that protect mice against lethal infections of influenza B virus, report scientists at Washington University School of Medicine in St. Louis and Icahn School of Medicine at Mount Sinai. Together with an antibody that targets the other major kind of influenza viruses that infect people -- influenza A -- these antibodies potentially could form the basis of a broad-spectrum flu drug that could treat almost all flu cases.
Contributor : Lisa E WagarSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTonsil organoid cultures were prepared from one donor and stimulated with live-attenuated influenza vaccine (LAIV) or left unstimulated. Cells were harvested on the days described below, total T and B cells were sorted, and cells were sequenced using the BD Rhapsody platform with a targeted set of immune-related genes, BCR, and TCR repertoire analysis.
Authors: Fattorini L, Creti R, Palma C, Pantosti A, Unit of Antibiotic Resistance and Special Pathogens, Unit of Antibiotic Resistance and Special Pathogens of the Department of Infectious Diseases, Istituto Superiore di Sanità, Rome Abstract Current literature shows that secondary bacterial infections, although less frequent than in previous influenza pandemics, affect COVID-19 patients. Mycoplasma pneumoniae, Staphylococcus aureus, Legionella pneumophila, Streptococcus pneumoniae, Haemophilus and Klebsiella spp. are the main species isolated. Of note, Mycobacterium tuberculosis-COVID-19 coinfections are al...