Comparison of Nonimage- and Fluoroscopy-Guided Interlaminar Epidural Block: A Matched Paired Analysis in the Same Individuals.
Conclusions: In this study, both blind and image-guided L-ESI techniques included similar extents of postprocedural outcomes and complications. Physicians should consider the risks associated with the two different techniques overall and develop ways to individualize the procedure to decrease the risk of complications and improve the positive outcomes of lumbar epidural steroid injections. PMID: 31065303 [PubMed - in process]
Conclusion Improvement of QOL of patients with head and neck cancer is a long process, which is associated with the clinical and demographic characteristics of patients. Implications for Practice Focusing nursing practice on shoulder and neck function rehabilitation, incision care, and pain management could positively affect QOL among patients with head and neck cancer treated by surgery.
ConclusionsThe algorithm produces plausible analyses of medication errors in older people, pointing to established areas of therapeutic deficiencies. Though individual recommendations exist, the algorithm cannot employ the full potential of FORTA as important details (e.g., blood pressure values, pain intensity) are not (yet) included. However, it seems capable of detecting medication problems in large cohorts —FORTA-EPI (Epidemiological) is designed to support epidemiological analyses, e.g., on comparisons of large cohorts, interventional impact, or longitudinal trends.
ConclusionsThe quality of pain management for fracture patients on skin traction is not up to the required level. The uncontrolled level of pain negatively affected patients’ physical status and general wellbeing.
Abstract BACKGROUND: As opioid abuse and addiction have developed into a major national health crisis, prescription of opioids for pain management has become more controversial. However, opioids do help some patients by providing pain relief and improving the quality of life. To better understand the addictive properties of opioids under chronic pain conditions, we used a conditioned place preference (CPP) paradigm to examine the rewarding properties of morphine in rats with persistent nociception. METHODS: Spared nerve injury (SNI) model was used to induce persistent nociception in rats. Nociceptive behavior...
CONCLUSIONS: This retrospective study with propensity-matched cohorts showed that cannabinoid use was associated with higher pain scores and a poorer quality of sleep in the early postoperative period in patients undergoing major orthopedic surgery. PMID: 31425232 [PubMed - in process]
Abstract Migraine is one of the most common neurological disorders which poses significant socioeconomic burden worldwide. Neuroinflammation and oxidative stress both play important roles in the pathogenesis of migraine. Human urinary kallidinogenase (UK) is a tissue kallikrein derived from human urine. Increasing evidence suggests that UK may protect against ischemic stroke, but UK's treatment potential against migraine remains to be explored. Immortal BV-2 murine microglial cells were treated with UK (125 nM, 250 nM, and 500 nM) and then given lipopolysaccharides (LPS, 1000 ng/mL). Ce...
Background: Cellulitis is an infection of the skin and subcutaneous tissue presenting with erythema, swelling, warmth, and pain. It is a common cause of skin and soft tissue infections, resulting in 650,000 hospital admissions per year in the United States alone. Antibiotic choice during hospitalization and on discharge is complicated by increasing concern about antibiotic-resistant bacteria, resulting in use of anti-MRSA antibiotics or broad-spectrum antibiotics. The Infectious Diseases Society of America has published guidelines for management of cellulitis, though whether these guidelines are implemented in everyday practice is unknown.
Background: Postherpetic neuralgia (PHN) is a neuropathic pain syndrome persisting or resuming after resolution of the herpes zoster (HZ) inflammatory rash. There is no consensus on best treatment, options for which are primarily pharmacologic and aimed at pain management
Opioid abuse has become a critical threat to individuals and communities in the U.S. Unfortunately, physicians and other health care providers may unintentionally be contributing to the epidemic, as prescription opioid use often precedes opioid misuse, abuse, and addiction. Adequate pain management, however, remains an integral component of patient-centered care, particularly for surgical procedures. The purpose of this study is to characterize opioid prescription patterns among Mohs surgeons, to analyze how these practices may vary based on procedural volume, and to compare these practices to those of nonsurgical dermatol...
Background: Nonmelanoma skin cancer (NMSC) includes basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) and are the most common skin cancers in the world. This term also encompasses more rare, but aggressive tumors such as sebaceous carcinoma. Many NMSC are detected and treated in the earlier stages of development, however, if left untreated, NMSC can grow to become large, ulcerating, locally destructive, and malignant tumors that may cause functional impairment, significant pain, and bleed frequently.