Exosomes expressing thyrotropin receptor ameliorate autoantibody-mediated stimulation of cyclic adenosine monophosphate production.

CONCLUSIONS: Our results suggest that exosomes expressing TSHR may be secreted from normal and cancerous thyroid cells. In thyroid gland of patients with GD, TSHR exosomes may exert a decoy effect by sequestering autoantibody, thereby ameliorating autoantibody-mediated activation of thyroid function. PMID: 31062662 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research