700 Pregnancy-Related Deaths Annually

CDC: 700 Pregnancy-Related Deaths Annually, Most Preventable
Source: eMedicineHealth.com - Category: General Medicine Source Type: news

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This study seeks to investigate whether paternal VPA exposure in rodents triggers behavioral and epigenetic alterations in offspring. The results show that paternal VPA exposure impairs object cognitive memory, suppresses the hyperactivity evoked by an NMDA receptor antagonist in male and female offspring, and disturbs sensorimotor gating in only females. In addition, since VPA is well known as an inhibitor of histone deacetylases, we examined the levels of acetylated histone H3 in the frontal cortex and hippocampus in the offspring of VPA-exposed sires. Interestingly, paternal VPA exposure down-regulates the levels of ace...
Source: Neurotoxicology and Teratology - Category: Toxicology Source Type: research
Publication date: Available online 19 September 2019Source: Reproductive BioMedicine OnlineAuthor(s): María Cruz, Diana Alecsandru, Juan Antonio García-Velasco, Antonio RequenaAbstractResearch questionGranulocyte colony-stimulating factor (G-CSF) acts on reproductive function at different stages, but its effects on the early stages of embryo development are unknown. The aim of this study was to assess the effect of G-CSF administration during treatment with assisted reproductive technologies (ART) and early pregnancy on newborns.DesignRetrospective study in women undergoing egg donation treatment, with a stud...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
ConclusionsFrozen embryo transfer was an independent risk factor of pre-eclampsia in assisted reproductive technology. The high ovarian response may also increase the risk of pre-eclampsia. The embryo stage at transfer was not related to the risk of pre-eclampsia.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
ConclusionPoor health hygiene, inadequate sanitation and unsafe drinking water facilities were found to be the underlying causes of Malnutrition. Most of the children and pregnant women in the study were poor in nutritional status. There is an urgent need for developing a program such as skills-based nutrition education and healthy eating habit.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
Over the past decade, increased use and misuse of opioids during pregnancy have resulted in more than a 5-fold increase in neonatal opioid withdrawal syndrome (NOWS). In 2014, more than 8 out of every 1000 births were affected by maternal opioid abuse, which has created an urgent need for methods to accurately detect, monitor, and treat symptoms of neonatal opiate withdrawal. Current methods of NOWS assessment are based on behavioral findings of irritability, tachypnea, crying, and hyperphagia, and are inherently subjective.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: The Editors' Perspectives Source Type: research
Publication date: Available online 22 October 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Angelo Sirico, Antonio Lanzone, Ilenia Mappa, Laura Sarno, Maciej SÅ‚odki, Dario Pitocco, Fulvio Zullo, Giuseppe Maria Maruotti, Giuseppe RizzoAbstractObjectiveEarly pregnancy models for prediction of GDM have been proposed, mostly using anamnestic and biochemical parameters. The aim of our study was to evaluate the strength of association of first trimester fetal heart rate (FHR) in predicting the development of gestational diabetes (GDM).Study designWe considered in our analysis sing...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Publication date: Available online 22 October 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Zheng Fei, Xin Xin, He Fei, Cui YuechongAbstractBackgroundIntrauterine adhesions are a severe complication after miscarriage. Hyaluronic acid gel has been used to prevent intrauterine adhesions after miscarriage.ObjectiveTo systematically evaluate the efficacy of adjuvant therapy with hyaluronic acid gel to prevent intrauterine adhesions after miscarriage.Search strategyThe Cochrane Library, Embase and PubMed databases were searched for articles published before 31 July 2018 using the ...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
This study systematically reviews the literature, aiming to define the value of sperm DNA fragmentation measurement in predicting clinical pregnancy outcome in couples undergoing intra-uterine insemination From inception until March 2018, the relevant databases were searched for studies investigating the relationship between sperm DNA fragmentation as measured by SCSA, TUNEL, SCD or Comet assay and pregnancy outcome after IUI. The Quality in Prognosis Studies (QUIPS) tool was utilized for quality assessment. This review is reported according to the 2009 PRISMA statement.The literature search resulted in 433 studies of whic...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
ConclusionsCauses of fetal demise at the end of the second trimester differ little from causes of stillbirth. There is value in using placental histology in late second trimester miscarriages to try to identify the cause of demise.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
ConclusionWe conclude that isolated HELLP syndrome is rare and seems to be a particular entity expressing a different angiogenic behaviour compared to classical PE or PE associated with HELLP syndrome.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
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