Bismuth Concentrations in Patients Treated in Real-Life Practice with a Bismuth Subcitrate-Metronidazole-Tetracycline Preparation: The SAPHARY Study

ConclusionsIn this study measuring blood bismuth concentrations in real-life practice, in    50 μg/L. No serious neurological adverse events were observed.Study registrationEU-PAS register EUPAS3142; ENCePP study seal.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research

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FDA QIDP and Fast Track Designations Signify Significant Milestones in Allergan Commitment to Addressing Unmet Medical Needs in the Treatment of Antibiotic Resistant Infections DUBLIN, Nov. 11, 2019 -- (Healthcare Sales &Marketing Network) -- Allergan... Biopharmaceuticals, FDA Allergan, ATM-AVI, aztreonam, avibactam
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
Conclusions. The applied diagnostic criteria had no significant effect on the reported rate of ABPA prevalence. PMID: 31702121 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Authors: Authried G, Prasad SC, Rasmussen ER, Bygum A Abstract Summary: A subset of patients with angioedema (AE) and urticaria has histamine releasing autoantibodies. The histamine release test (HR-test) has been used as a tool in chronic urticaria to define the autoimmune subgroup and may possibly guide the clinician to a more personalized therapy, like omalizumab and cyclosporine. The prevalence and value of positive histamine releasing autoantibodies in monosymptomatic AE is sparsely described in the literature. The purpose of this study was to report the prevalence of positive histamine releasing autoantibodie...
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Publication date: Available online 9 November 2019Source: Food ControlAuthor(s): Yanbo Wang, Qinqin Qi, Jinru Zhou, Huan Li, Linglin FuAbstractFish has been recognized as one of the “Big-Eight” allergenic food sources with parvalbumin (PV) being one of the major allergens. Here, we report a novel immunomagnetic beads-derived enzyme-linked immunosorbent assay (ELISA) method which employ antibody functionalized graphene oxide (GO) and gold nanoparticles (AuNPs) to amplify the detection signal of PV. The GO and AuNPs are modified with monoclonal antibody (mAb) and HRP-labeled secondary antibody respectively to det...
Source: Food Control - Category: Food Science Source Type: research
AbstractPBC is a chronic progressive autoimmune disorder involving the destruction of intrahepatic small bile ducts, cholestasis, fibrosis, and ultimately cirrhosis if left untreated. It is largely driven by the autoimmune response, but bile acids and the intestinal microbiota are implicated in disease progression as well. The only drugs licensed for PBC are UDCA and OCA. UDCA as a first-line and OCA as a second-line therapy are safe and effective, but the lack of response in a significant portion of patients and inadequate control of symptoms such as fatigue and pruritus remain as concerns. Liver transplantation is an end...
Source: Clinical Reviews in Allergy and Immunology - Category: Allergy & Immunology Source Type: research
In conclusion, the present study cloned and expressed the Der f TEF 2 gene, and the recombinant protein exhibited immunogenicity, providing a theoretical bases, and references, for the diagnosis and treatment of allergic disease. PMID: 31702815 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Using electronic cigarettes or vaping is associated with lung injury that can appear as nonspecific findings on chest radiography and CT, researchers report.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news
ConclusionChildren with asthma with exacerbations compared to asthma children without exacerbations are characterized by increased airway obstruction since infancy through childhood. The airway obstruction is a fixed trajectory without progression due to exacerbations, suggesting that exacerbations are a consequence rather than a cause of diminished airway caliber in childhood.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 8 November 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): David Langton, Wei Wang, Joy Sha, Alvin Ing, David Fielding, Nicole Hersch, Virginia Plummer, Francis ThienAbstractBackgroundWhilst it is established that not all patients respond to bronchial thermoplasty (BT), the factors that predict response/non-response are largely unknown.ObjectivesThe aim of this study was to identify baseline factors that predict clinical response.MethodsThe records of 77 consecutive patients entered into the Australian Bronchial Thermoplasty Register were examined for bas...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Authors: Cardoso BK, Farinha SM, Martins M, Lobão B, Tomaz E, Inácio F PMID: 31703189 [PubMed - in process]
Source: Acta Medica Portuguesa - Category: General Medicine Tags: Acta Med Port Source Type: research
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