Propofol protects against high glucose-induced endothelial adhesion molecules expression in human umbilical vein endothelial cells

Conclusion: Propofol, via decreasing O2.- accumulation, down-regulating PKCbeta2 Ser660 phosphorylation and PKC as well as NF-kappaB activity, attenuated high glucose-induced endothelial adhesion molecules expression and mononuclear-endothelial adhesion.

http://www.cardiab.com/content/12/1/13

Source: Cardiovascular Diabetology - January 11, 2013 Category: Cardiology Authors: Minmin ZhuJiawei ChenHui JiangChanghong Miao Source Type: research