Author Correction: Pre-eclampsia: pathogenesis, novel diagnostics and therapies
Author Correction: Pre-eclampsia: pathogenesis, novel diagnostics and therapiesAuthor Correction: Pre-eclampsia: pathogenesis, novel diagnostics and therapies, Published online: 08 May 2019; doi:10.1038/s41581-019-0156-1Author Correction: Pre-eclampsia: pathogenesis, novel diagnostics and therapies
Conclusion With a changing demographic profile of preeclampsia, older women accounted for an increasing proportion of preeclampsia and related adverse outcomes. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | Full text
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Miscarriage can be a devastating outcome for couples and most miscarriages are unexplained. Many adverse obstetric outcomes are thought to be inherited such as pre-eclampsia, preterm birth and growth restriction. It is possible these conditions could share similar pathophysiological mechanisms with miscarriage such as endothelial dysfunction. Therefore, it was hypothesised that there could be a susceptibility to miscarriage transmitted from mother to daughter.
Publication date: Available online 16 August 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Andrew Sharp, Richard Jackson, Christine Cornforth, Jane Harrold, Mark A. Turner, Louise Kenny, Philip N. Baker, Edward D. Johnstone, Asma Khalil, Peter von Dadelszen, Aris T. Papageorghiou, Zarko AlfirevicAbstractBackgroundSevere early-onset fetal growth restriction (FGR) predisposes to fetal death, neonatal death, neonatal morbidity and neurodisability. The use of placental biomarkers has been proposed for risk stratification in pre-eclampsia, but they could be equally useful in fetal...
CONCLUSION: Thrombophilias are inherited or acquired predispositions to vascular thrombosis and have been associated with thrombosis of the arteriovenous fistula. Patients on hemodialysis with recurrent vascular access thrombosis and presence of thrombophilia should be evaluated about the need for anticoagulant therapy with a vitamin K antagonist. PMID: 31419276 [PubMed - as supplied by publisher]
ConclusionWe found that the PC, MPV, and PC/MPV may be changed in atypical PE patients who did not have significant PE symptoms. Our results indicated that it could be a diagnostic method to predict atypical PE during pregnancy. PC/MPV and the other platelet parameters can play a role in predicting the development of atypical PE, leading to better diagnosis and management of atypical PE.
Background: Women living with HIV have a higher risk of adverse birth outcomes, but questions remain regarding their specific risk factors for stillbirth and the extent to which maternal HIV is associated with stillbirth. Methods: Using data on pregnant women with HIV reported within population-based surveillance in the United Kingdom/Ireland, we described stillbirth rates in 2007–2015 stratified by type of antiretroviral therapy (ART) and evaluated risk factors using Poisson regression. General population stillbirth rates by maternal world region of origin were derived from national annual birth statistics, and...
Publication date: 17–23 August 2019Source: The Lancet, Volume 394, Issue 10198Author(s): Theresa Anne Lawrie, Calcium and Pre-eclampsia Study Group
Publication date: 17–23 August 2019Source: The Lancet, Volume 394, Issue 10198Author(s): Yuto Maeda, Yosuke Suzuki, Kana Yamamoto, Tetsuya Tanimoto
Abstract Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder of premenopausal women worldwide and is characterized by reproductive, endocrine, and metabolic abnormalities. The clinical manifestations of PCOS include oligomenorrhea or amenorrhea, hyperandrogenism, ovarian polycystic changes, and infertility. Women with PCOS are at an increased risk of suffering from type 2 diabetes; me\tabolic syndrome; cardiovascular events, such as hypertension, dyslipidemia; gynecological diseases, including infertility, endometrial dysplasia, endometrial cancer, and ovarian malignant tumors; pregnancy complication...