Increased Levels of Kynurenic Acid in the Cerebrospinal Fluid in Patients with Hydrocephalus.

CONCLUSION: The aging process is related to elevated CSF levels of KYNA, L-KYN, and L-TRP levels. There are significant differences in clinical parameters between the two forms of hydrocephalus and these differences might have diagnostic utility. The occurrence of dementia in patients with either form of hydrocephalus might be at least partly related to elevated KYNA levels in the CNS and/or periphery.
PMID: 31059212 [PubMed - in process]

Source: Neuro-Signals - May 8, 2019 Category: Neurology Authors: Kepplinger B, Baran H, Kronsteiner C, Reuss J Tags: Neurosignals Source Type: research