Are Sleeping Pills Safe? Here ’s What Research Says

According to the latest numbers, roughly 9 million Americans — 4% of U.S. adults — use prescription sleep aids, or medications that can help with insomnia and other sleep issues. And now, some of the most popular prescription sleep drugs must carry stronger safety warnings. In April, the Food and Drug Administration (FDA) mandated black-box warnings — which the agency uses to “call attention to serious or life-threatening risks” — on three sedative-hypnotic sleep aids: eszopiclone (often sold under the brand name Lunesta), zaleplon (Sonata) and zolpidem (Ambien). Hypnotic drugs, which are used to prompt or maintain sleep, have been connected to 20 reported deaths and 46 non-fatal but serious injuries, according to the FDA. Injuries included accidental overdoses, falls and near-drownings, while deaths were caused by carbon monoxide poisoning, hypothermia, car accidents, apparent suicide and more, the FDA said. “While these incidents are rare, they are serious and it’s important that patients and health care professionals are aware of the risk,” acting FDA Commissioner Dr. Ned Sharpless said in a statement. Here’s what the research says about the safety — and potential dangers — of prescription sleep aids. Sleeping pills have well-documented side effects The side effects of sleeping pills vary by medication, but they can include dizziness, headache, gastrointestinal issues, prolonged drowsiness, allergic r...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Drugs Source Type: news

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This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Daria V. Berdnikova RNA is an emerging drug target that opens new perspectives in the treatment of viral and bacterial infections, cancer and a range of so far incurable genetic diseases. Among the... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
Immunotherapy has led to a higher survival rate among different oncological disease groups but also associated with adverse-related events in multiple organ systems. Immunotherapy-related musculoskeletal weakness often results in a loss of cancer survivors’ physical function, ultimately impacting their independence and quality of life. This is a retrospective study of 24 cancer patients who were treated with immunotherapy either alone or in conjunction with other oncological treatments. Twelve subjects (50%) were found to have acute inflammatory demyelinating polyradiculopathy/Guillain-Barré syndrome, six (25%...
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Brief Report Source Type: research
Lucid is focused on patients with gastroesophageal reflux disease, also known as chronic heartburn or acid reflux, who are at risk of developing esophageal cancer.
Source: Health Care News Headlines - Category: Health Management Authors: Source Type: news
Lucid is focused on patients with gastroesophageal reflux disease, also known as chronic heartburn or acid reflux, who are at risk of developing esophageal cancer.
Source: Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
AbstractGrowing evidence has revealed that circular RNAs (circRNA) play critical roles in cancer progression. Here, we examined the function of a novel circRNA, Circ_0005795, in basal cell carcinoma (BCC) and explored the possible molecular mechanism. Nodular BCC and adjacent non-tumor tissues derived from 30 patients and 2 BCC cell lines were applied to analyze gene expression. Circ_0005795 loss- and gain-of-function were constructed to investigate BCC progression. Nuclear and cytoplasmic fractionation and luciferase assay were carried out to determine cellular localization and molecular interaction of Circ_0005795. Circ_...
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research
THE MENOPAUSE transition is defined as the time leading up to a woman's final period. It is usually characterised by an onslaught of bothersome symptoms, including insomnia. Researchers studying the effects of diet on menopause believe some foods may exacerbate sleeplessness.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Diagnostic imaging with 68Ga-PSMA-11 PET detects about 80% of pelvic nodal metastases at initial staging of intermediate to high-risk prostate cancer, but a negative scan does not rule out the need for dissection, researchers say.Reuters Health Information
Source: Medscape Radiology Headlines - Category: Radiology Tags: Hematology-Oncology News Source Type: news
The first report of a median overall survival (OS) exceeding 5 years in a phase 3 trial for advanced breast cancer comes from the MONALESSA-2 trial with ribociclib and letrozole.Medscape Medical News
Source: Medscape Hematology-Oncology Headlines - Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Despite adjustments to the US Preventive Services Task Force lung cancer screening criteria, disparities in eligibility between racial and ethnic minorities and white patients have not changed, a new study suggests.Reuters Health Information
Source: Medscape Radiology Headlines - Category: Radiology Tags: Hematology-Oncology News Source Type: news
AbstractMacrophages show two main phenotypes, the M1-type (pro-inflammatory) and the M2-type (anti-inflammatory). The purpose of this research was to investigate the regulatory effect of carbon monoxide releasing molecule-3 (CORM-3) on LPS-induced macrophage polarization. LPS-induced RAW264.7 cells were exposed to CORM-3 for 24 h. Polarization of cells was checked by flow cytometry; expression of M1 or M2 macrophage-related factors and NF- κB signaling factors was examined by RT-PCR, ELISA, and Western blot. Male C57 mice were divided into three groups: normal group; periodontitis group, where experimental periodonti...
Source: Inflammation - Category: Allergy & Immunology Source Type: research
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