Treating asymptomatic MRSA on discharge from hospital reduces risk of later infection

This study suggests that patients who test positive for MRSA in hospital should be treated after discharge, even if they show no symptoms, in order to reduce the risk of later MRSA infection. Decolonisation treatment is most effective when patients follow the regimen exactly. However, the intensive programme of daily products, and the length of the treatment, may make it difficult for patients to stick to when in their own homes, without medical supervision.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

Related Links:

ConclusionsWe reported a low rate of MRSA colonization in infants admitted to our NICU, without impact on mortality and inhospital morbidity. Further large-scale studies are needed to understand the implications and cost-effectiveness of active MRSA surveillance.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Methicillin-resistantStaphylococcus aureus (MRSA) has become a serious problem, forcing doctors to turn to antibiotics other than penicillin or penicillin derivatives, or to different drug cocktails, which are often less effective in treating hospital and community based infections.
Source: Medical Research Council General News - Category: Research Source Type: news
(University of Cambridge) Some MRSA infections could be tackled using widely-available antibiotics, suggests new research from an international collaboration led by scientists at the University of Cambridge and the Wellcome Sanger Institute.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
In this study, we developed a composite material to combine silver nanoparticle, a commonly used disinfectant, with a potent photosensitizer for aPDT. Interestingly, we found the photosensitizer activated the silver nanoparticles into silver ions under light illumination. At the same time, silver nanoparticles enhanced the generation of ROS by the photosensitizer. Together, the two components activates each other, leading to remarkable antimicrobial efficacy against not only gram-positive and -negative bacteria, but also drug resistant bacteria (Methicillin Resistant S. aureus, MRSA). Such antimicrobial effect was further ...
Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
Abstract Burgeoning antibiotic resistance among bacterial pathogens necessitates the alternative treatment options to control the multidrug-resistant bacterial infections. Plant secondary metabolites, a significant source of structurally diverse compounds, posses several biological activities. The present study was designed to investigate the anti-virulence potential of least explored phytocompound 2-hydroxy-4-methoxybenzaldehyde (HMB) against methicillin-resistant Staphylococcus aureus (MRSA) and its clinical isolates. The minimum inhibitory concentration of HMB was found to be 1024 μg/ml. HMB at sub-MIC ...
Source: Applied Microbiology and Biotechnology - Category: Microbiology Authors: Tags: Appl Microbiol Biotechnol Source Type: research
Publication date: Available online 20 June 2019Source: Carbohydrate PolymersAuthor(s): Xiao Yang, Wen Liu, Guanghui Xi, Mingshan Wang, Bin Liang, Yifen Shi, Yakai Feng, Xiangkui Ren, Changcan ShiAbstractIt is important to control immediate hemorrhage and prevent infection simultaneously in the wound management. However, most of hemostatic materials are associated with low efficiency of hemostasis, poor biocompatibility and lack of antimicrobial properties. A kind of starch-based macroporous sponges (KR-Sps) immobilized covalently with antimicrobial peptide KR12 using highly efficient thiol-ene photo click reaction were dev...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Authors: Wang S, Li Y, Xue F, Liu J, Yang W, Zhang J, Glenschek-Sieberth M, Lyu Y Abstract We compared the kill-curve activity of tedizolid and linezolid at clinically relevant (total or free plasma, lung) concentrations against methicillin-resistant Staphylococcus aureus (MRSA) and penicillin-resistant Streptococcus pneumoniae (PRSP) isolated from Chinese patients. Tedizolid had greater in vitro potency than linezolid against staphylococci, streptococci and enterococci species (tedizolid minimum inhibitory concentration (MIC) range: ≤ 0.016-0.5 µg/mL; linezolid MIC range: 0.25-2 µg/mL)...
Source: Journal of Chemotherapy - Category: Cancer & Oncology Tags: J Chemother Source Type: research
Abstract Toward the search of new antibacterial agents to control methicillin-resistant Staphylococcus aureus (MRSA), a class of new norfloxacin-1,3,4-oxadiazole hybrids were designed and synthesized. Antibacterial activities against drug-sensitive bacteria S. aureus and clinical drug resistant isolates of MRSA were evaluated. Compound 5k exhibited excellent antibacterial activities against S. aureus (MIC: 2 μg/mL) and MRSA1-3 (MIC: 0.25-1 μg/mL). The time-kill kinetics demonstrated that compound 5k had an advantage over commonly used antibiotics vancomycin in killing S. aureus and MRSA. Moreover, compou...
Source: European Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Authors: Tags: Eur J Pharm Sci Source Type: research
In this study, we evaluated the antimicrobial activity of the extracts from herbal plant Persicaria pensylvanica’s flower, leaf, stem, and root. This plant is also known by a common name Pennsylvania smartweed. The antimicrobial effect of the extracts was tested using minimum inhibitory concentration (MIC) and minimum bacteriocidal concentration (MBC) methods in comparison with tetracycline, a commercial antibiotic.ResultsWe found that extract from P. pensylvanica kills bovine mammary glands pathogenic S. aureus strain Newbould 305. The minimum inhibitory concentration (MIC) breakpoints for extracts from the flower, ...
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
E-101 solution is a first-in-class myeloperoxidase-mediated antimicrobial developed for topical application. It is composed of porcine myeloperoxidase (pMPO), glucose oxidase (GO), glucose, sodium chloride, and specific amino acids in an aqueous solution. Once activated, the reactive species hydrogen peroxide (H2O2), hypochlorous acid, and singlet oxygen are generated. We evaluated the treatment effects of E-101 solution and its oxidative products on ultrastructure changes and microbicidal activity against methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli. Time-kill and transmission electron microscop...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Bacterial Infections Source Type: research
More News: Health | Hospitals | Infectious Diseases | MRSA | Study | Superbugs