Diagnostic Value of Histological Analysis of Punch Biopsies in Suspected Cutaneous Buruli Ulcer: A Study on 32 Cases of Confirmed Buruli Ulcer in Cameroon

Conclusion: Punch biopsies help in establishing the correct diagnosis of BU and also in the differential diagnosis of chronic ulcers. The main histological feature for BU is diffuse coagulative necrosis of subcutaneous tissue, with acid-fast bacilli detected by ZN stain.Dermatopathology 2019;6:28 –36
Source: Dermatopathology - Category: Pathology Source Type: research

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CONCLUSIONS: Prevalence and comorbidity of major MH conditions is high in veterans referred for geriatric MH services. Future work will examine challenges faced by non-specialty providers in caring for older veterans, with the goal of developing targeted educational and clinical interventions to better address aging veterans' MH needs. PMID: 31621886 [PubMed - as supplied by publisher]
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
In this study, it was aimed to determine the bioactive compounds and volatile aroma compounds of the sour cherry vinegar, and to investigate the usability of concentrated juice instead of the fresh fruit juice in vinegar production. And, two sour cherry vinegars were produced using juices prepareted fresh fruit (FSCJ) and concentrate juice (CSCJ), analyzed for functional and organoleptic aspects. The finding shown that both vinegars produced have rich functional compounds (gallic and chlorogenic acids) and volatile aroma compounds, and sour cherry is ideal for vinegar production. However, the vinegar produced using the CSC...
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 15 October 2019Source: Food ChemistryAuthor(s): Sara Muñiz-Calvo, Ricardo Bisquert, Sergi Puig, José Manuel GuillamónAbstractHydroxytyrosol (HT), which is a polyphenol with a high antioxidant power and many associated health benefits, has been found in wines. Wine yeasts are capable of producing high amounts of the higher alcohol tyrosol, which is the precursor for HT synthesis. We have improved the ability of Saccharomyces cerevisiae to produce HT by heterologously expressing the HpaBC enzyme complex of Escherichia coli, which hydroxylates tyrosol into HT. By overexp...
Source: Food Chemistry - Category: Food Science Source Type: research
This article aims to show that the terms “use” and “abuse” conventionally mobilized to speak of good and bad consumption are not able to exhaust the range of possibilities in terms of alcohol drinking behaviors understanding. Indeed, only the consideration of contextual and identity dynamics can allow us to understand with accuracy the relationship to this substance.Graphical abstract
Source: Current Opinion in Food Science - Category: Food Science Source Type: research
Publication date: Available online 16 October 2019Source: Enzyme and Microbial TechnologyAuthor(s): Chae Gyeong Park, Jin Ju Kim, Hyung Kwoun KimAbstractCastor oil extracted from castor bean has antibacterial property, and has been used in various folk remedies. The major structural component of castor oil, ricinoleic acid, has actual antibacterial activity. Some phenolic compounds derived from plants have antioxidant property. Among them, vanillyl alcohol from vanilla bean has strong antioxidant activity. As vanillyl alcohol has low solubility in hydrophobic solvents and castor oil has low solubility in hydrophilic solven...
Source: Enzyme and Microbial Technology - Category: Biotechnology Source Type: research
We present the case of a 30-year-old Bissau-Guinean man with HIV-2 infection known for 16 years, irregularly treated, admitted with two weeks of fever, diarrhoea and cutaneous lesions. Examination revealed multiple subcutaneous nodes, Molluscum contagiosum-like lesions, generalized lymphadenopathy and painful palpation of the left iliac fossa. Laboratory tests showed severe nonhaemolytic anaemia and CD4+ count of 9/mm3, with normal creatinine and hepatic enzymes. Chest roentgenogram was unremarkable and a research for Mycobacterium tuberculosis by GeneXpert® was negative. Nonetheless, given the lack of further diagnost...
Source: Journal of Medical Mycology - Category: Biology Source Type: research
We report on a whole-cell biocatalytic conversion of cyclohexanol to ε-caprolactone using the combination of an alcohol dehydrogenase (ADH) with two stability-improved variants (QM and M15) of the Baeyer-Villiger monooxygenase CHMO with special focus on process development at the 200 mM scale. Influence of parameters such as volumetric mass transfer co-efficient, stirrer speed and catalytic loading (amount of E. coli whole-cells expressing ADH and CHMO) on the process efficiency were studied and optimised. This resulted in over 98% conversion, a product titer of 20 g L–1 and an isolated product ...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
Publication date: Available online 16 October 2019Source: Catalysis CommunicationsAuthor(s): Jamal Rahimi, Reza Taheri-Ledari, Maryam Niksefat, Ali MalekiAbstractHerein, we present an organic–inorganic hybrid nanocomposite constructed of polyvinyl alcohol (PVA), iron oxide (Fe3O4), and 10% of silver nanoparticles (Ag NPs). First, a convenient in situ method is introduced for the preparation of this efficient catalytic system (Fe3O4/PVA-10%Ag). Further, we study the high catalytic performance for the reduction of nitrobenzene (NB) derivatives as a hazardous species of chemicals and the significant biological activity ...
Source: Catalysis Communications - Category: Chemistry Source Type: research
We report a high-yielding metal templated Cannizzaro reaction for converting symmetrical aromatic crown ether dialdehydes of various types [dibenzo and bis(meta-phenylene)] and sizes (20-32 atom rings) to acid-alcohol functionalized crown... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
CONCLUSION: The caregivers in this study have gained valuable knowledge and wisdom through caring for a child with FASD that can benefit health professionals and the broader community. Whilst the caregivers in this study have overcome challenges through developing and adapting their own strategies, support services providing tailored programs for caregivers when they first start caring for a child with FASD would be beneficial. Furthermore, formal respite was not utilised by the caregivers in this study due to safety issues, inconsistent parenting and interrupted routines, therefore investigation into training respite care...
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
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