Variant form of hairy cell leukemia

Mature lymphoid B ‐cell proliferations with hairy cells represent heterogeneous entities where specific diagnosis is difficult but important since it impacts therapeutic management. The clinical cases of variant hairy cell leukemia reported herein illustrate the persistence of a clear interest in the use of splenec tomy as a therapeutic alternative. Furthermore, ibrutinib appears to be a promising treatment in patients with relapsed/refractory disease. AbstractMature lymphoid B ‐cell proliferations with hairy cells represent heterogeneous entities where specific diagnosis is difficult but important since it impacts therapeutic management. The clinical cases of variant hairy cell leukemia reported herein illustrate the persistence of a clear interest in the use of splenec tomy as a therapeutic alternative. Furthermore, ibrutinib appears to be a promising treatment in patients with relapsed/refractory disease.

Source: Clinical Case Reports - May 5, 2019 Category: General Medicine Authors: Margaux Wiber, Elsa Maitre, Edouard Cornet, V éronique Salaün, Dina Naguib, Xavier Troussard Tags: CASE REPORT Source Type: research