Does Hormone Therapy for Prostate Cancer Raise Dementia Risk?

Title: Does Hormone Therapy for Prostate Cancer Raise Dementia Risk?Category: Health NewsCreated: 5/5/2019 12:00:00 AMLast Editorial Review: 5/6/2019 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news

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TUESDAY, July 9, 2019 -- Among elderly patients with prostate cancer, androgen deprivation therapy (ADT) exposure is associated with subsequent diagnosis of Alzheimer disease or dementia, according to a study published online July 3 in JAMA Network...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
In total, 13% of men who had received the therapy went on to develop Alzheimer's disease over eight years of follow-up, compared to 9%  who hadn't gotten the treatment, the study found.
Source: WebMD Health - Category: Consumer Health News Source Type: news
(University of Pennsylvania School of Medicine) A Penn study of more than 150,000 men with prostate cancer shows androgen deprivation therapy was associated with a higher likelihood of developing dementia when compared to patients who were not exposed to the treatment.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
In this study, we identify a link between members of the genus Veillonella and exercise performance. We observed an increase in Veillonella relative abundance in marathon runners postmarathon and isolated a strain of Veillonella atypica from stool samples. Inoculation of this strain into mice significantly increased exhaustive treadmill run time. Veillonella utilize lactate as their sole carbon source, which prompted us to perform a shotgun metagenomic analysis in a cohort of elite athletes, finding that every gene in a major pathway metabolizing lactate to propionate is at higher relative abundance postexercise. Us...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Alzheimer's disease may be a risk for older prostate cancer patients given hormone-blocking treatment
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Prostate cancer patients who received hormone-lowering therapy were at higher risk of developing dementia and Alzheimer's disease later on than men who didn't get this treatment, a large U.S. study finds.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Androgen deprivation therapy for prostate cancer is associated with an increased risk of Alzheimer ’s disease and other forms of dementia.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Alzheimer ' s Disease Prostate Cancer Dementia Hormones Source Type: news
(JAMA Network) Data for 154,089 older men diagnosed with prostate cancer were used to analyze the association between androgen deprivation therapy, a hormone-suppressing therapy used to treat prostate cancer, and subsequent diagnosis of Alzheimer disease or dementia. Of the men, 62,330 (average age 76) received androgen deprivation therapy within two years of being diagnosed with prostate cancer and 91,759 men (average age 74) didn't have such treatment.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Authors: Pundir CS, Deswal R, Yadav P Abstract The quantitative determination of sarcosine is of great importance in clinical chemistry, food and fermentation industries. Elevated sarcosine levels are associated with Alzheimer, dementia, prostate cancer, colorectal cancer, stomach cancer and sarcosinemia. This review summarizes the various methods for quantitative analysis of sarcosine with special emphasis on various strategies of biosensors and their analytical performance. The current biosensing methods have overcome the drawbacks of conventional methods. Sarcosine biosensors work optimally at pH 7.0 to 8.0 in t...
Source: Biomarkers - Category: Research Tags: Biomarkers Source Type: research
Abstract Prostate cancer is the most common form of cancer diagnosed in men. Androgen deprivation therapy (ADT) is commonly prescribed, with some estimates indicating over 50% of men with prostate cancer receive ADT at some point in their treatment. Men on ADT are typically otherwise healthy, with good long-term survival. However, consequences of androgen deprivation can include side effects that may include changes in cognition or onset of dementia. This review will describe what is known about ADT and changes in cognitive function, the possible connection with Alzheimer's disease, how to discuss this with patien...
Source: Urologic Oncology - Category: Urology & Nephrology Authors: Tags: Urol Oncol Source Type: research
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