Anti-estrogen Treatment in Endometrial Cancer: A Systematic Review

Conclusion: Tamoxifen or a combination of tamoxifen and progestin should be the preferred choice when selecting second line hormonal treatment because the RRs are similar to first line progestin treatment and the toxicity is low. The response can be optimized by selecting patients with endometrioid tumors and positive estrogen receptor status, which should be based on a pretreatment biopsy.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research