Modified Rheumatoid Arthritis Impact of Disease (RAID) Score, a Potential Tool for Depression and Anxiety Screening for Rheumatoid Arthritis

Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Khai-Jing Ng, Kuang-Yung Huang, Chien-Hsueh Tung, Bao-Bao Hsu, Cheng-Han Wu, Malcolm Koo, Chia-Wen Hsu, Ming-Chi Lu, Ning-Sheng Lai
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research

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ConclusionsFor RA patients, achieving the therapeutic target can result in better SWB than that of healthy controls. Financial status, self ‐assessment of health, psychological stress, and social network are also important determinants for the SWB of RA patients.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Conclusion: Natural recovery after TBI may include delayed onset of functional decline or early recovery, followed by progressive deterioration, and is negatively affected by medical comorbidities. Results contribute to the growing evidence that TBI is most appropriately treated as a chronic medical condition complicated by a variety of comorbid conditions.
Source: The Journal of Head Trauma Rehabilitation - Category: Neurology Tags: Original Articles Source Type: research
Publication date: Available online 22 August 2019Source: Journal of Clinical NeuroscienceAuthor(s): Bruno Kusznir Vitturi, Bruno Azeredo Coutinho Nascimento, Beatriz Rizkallah Alves, Felipe Sobolewski Carneiro de Campos, Dawton Yukito TorigoeAbstractBackgroundNeurological manifestations of Rheumatoid Arthritis (RA) are usually uncommon. However, a number of recent studies have reported that the burden of cognitive impairment in RA could be significant. We sought to explore the prevalence and clinical predictors of cognitive impairment in persons with RA.MethodsThis is a cross-sectional case-control study with patients with...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
The objective was to evaluate the impact of moderate-to-high intensity, aerobic and resistance exercise with person-centered guidance on fatigue, anxiety and depression, in older adults with RA. Comparisons were made between older adults (>  65 years) with RA taking part in a 20-week moderate-to-high intensity exercise at a gym (n = 36) or in home-based exercise of light intensity (n = 38). Assessments were performed at baseline, at 20 weeks, and at 52 weeks. Outcomes were differences in Multidimensional Fatigue Inventory (MFI-20), Visual Analog Scale Fatigue (VAS fatigu...
Source: Rheumatology International - Category: Rheumatology Source Type: research
CONCLUSIONS: Depression, disability and sleep disturbance appear to be the main factors explaining fatigue in patients with RA. Disease activity, pain, and personality seem to play only a secondary role, extroversion being the only personality trait associated with fatigue. These findings foster a shift in the paradigm of care towards a more holistic management of fatigue, integrating adjunctive therapies beyond measures targeted solely at disease remission. PMID: 31365331 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
AbstractIntroduction/objectivesPrimary Sj ögren’s syndrome (pSS) is a chronic systemic autoimmune disease. The aim of this study was to investigate the risk of five common psychiatrist-diagnosed disorders in patients with pSS.MethodUsing Taiwan ’s National Health Insurance Research Database, 688 patients with newly diagnosed pSS between 2000 and 2012 were identified. Two comparison cohorts were assembled, namely, 3440 patients without pSS and 1302 newly diagnosed patients with rheumatoid arthritis. The incidences of depressive disorder, anxiety disorder, bipolar disorder, sleep disorder, and schizophrenia ...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
AbstractSocial Signal Transduction Theory of Depression is a biologically plausible, multi-level theory that describes neural, physiologic, molecular, and genomic mechanisms that link experiences of social-environmental adversity with internal biological processes that drive depression pathogenesis, maintenance, and recurrence. Central to this theory is the hypothesis that interpersonal stressors involving social threat (e.g., social conflict, evaluation, rejection, isolation, and exclusion) upregulate inflammatory processes that can induce several depressive symptoms, including sad mood, anhedonia, fatigue, psychomotor re...
Source: Psychopharmacology - Category: Psychiatry Source Type: research
AbstractObjectivesTo investigate potential risk factors of peripheral neuropathy (PN) in rheumatoid arthritis patients (RA).MethodsEighty-eight patients with RA were enrolled in this study, including patients with PN (n = 44; 28 patients with multiple nerves (MN) involvement and 16 patients with single nerve (SN) involvement) and without (n = 44) peripheral neuropathy were enrolled. Their clinical features were comprehensively collected including symptoms/signs, lab results, electromyogram data.T test or chi-squared test and further binary regression analysis were used to explore risk factors ba...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
ConclusionLow DAS28 and HAQ scores at baseline, anti-CCP were positive predictors of SR. Instead of 6  months, remission duration for ≥ 12 months would probably help us to predict SR independently from the chosen criteria; Boolean or SDAI.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Publication date: September 2019Source: Biomedicine &Pharmacotherapy, Volume 117Author(s): Jiashu Lu, Yaoying Ma, Jingjing Wu, Huaxing Huang, Xiaohua Wang, Zhuo Chen, Jinliang Chen, Haiyan He, Chao HuangAbstractAndrographolide is compound extracted from Andrographis paniculata (A. paniculata), a traditional herb that has been used in ancient China and other parts of eastern Asia to treat an array of disorders, such as cancer, rheumatoid arthritis, diarrhea, upper respiratory tract infection, and laryngitis, for a very long history. The mechanisms of action of andrographolide in disease prevention and/or therapy include...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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