Antitumor Effects of Chrysophanol in Malignant Optic Nerve Meningioma Cell Lines are Mediated via Caspase Activation, Induction of Mitochondrial Mediated Apoptosis, Mitochondrial Membrane Depolarization and Targeting the Mitogen-Activated Protein Kinase Signaling Pathway

Conclusion: The findings of the present study suggest that chrysophanol may prove beneficial in the treatment of malignant meningioma of optic nerve.Key Message: The study revealed the anticancer potential of chrysophanol against the malignant optic nerve meningioma.Pharmacology 2019;104:28 –35
Source: Pharmacology - Category: Drugs & Pharmacology Source Type: research