The impact of white matter hyperintensities on the structural connectome in late-life depression: Relationship to executive functions

ConclusionsIn LLD, WMH are associated with region-specific disruptions in cortical and subcortical gray matter areas involved in attentional aspects of cognitive control systems and sensorimotor processing, which in turn are associated with slower processing speed, and reduced attentional set-shifting.Clinical trials registrationhttps://clinicaltrials.gov/ct2/show/NCT01728194
Source: NeuroImage: Clinical - Category: Radiology Source Type: research