Sex hormone binding globulin for prediction of gestational diabetes mellitus in pre-conception and pregnancy: A systematic review

Gestational diabetes mellitus (GDM) affects approximately 1-24% of pregnancies [1]. It is defined as glucose intolerance that is recognized for the first time during pregnancy [2]. GDM is associated with adverse complications for the mother (pre-eclampsia, cesarean section) and the fetus (dystocia, large for gestational age, and macrosomia) [3-5]. Early prediction of GDM can lead to appropriate interventions such as lifestyle changes or pharmacological means to reduce adverse health impact. There is no standard agreed-upon screening protocol for GDM.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Tags: Review Source Type: research

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Marjon E. Feenstra1†, Mirthe H. Schoots2†, Torsten Plösch1, Jelmer R. Prins1, Sicco A. Scherjon1, Albertus Timmer2, Harry van Goor2 and Sanne J. Gordijn1* 1Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands 2Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands Objective: Management of late fetal growth restriction (FGR) is limited to adequate fetal monitoring and optimal timing of delivery. The Disproportionate Intrauterine Growth Intervention ...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
INTRODUCTION: Pregnancy is a risk factor for venous thromboembolism (VTE) and VTE affects 1 in 500 to 1 in 2000 pregnancies. Up to 30-50% of women with pregnancy-associated VTE may have an inherited thrombophilia but this does not completely explain the thrombosis risk. Clinical risk factors for VTE including multiple births, inflammatory bowel disease, sickle cell disease, diabetes, increased maternal age, stillbirth, and smoking have been identified in relatively small cohorts. We conducted this large case-control study to identify patient and pregnancy-associated risk factors for VTE during pregnancy or within 6 weeks p...
Source: Blood - Category: Hematology Authors: Tags: 331. Pathophysiology of Thrombosis: Poster III Source Type: research
ConclusionT1DM in pregnancy is associated with adverse pregnancy outcomes compared to the general population. Reducing gestational weight gain and improving glycaemic control might improve pregnancy outcomes.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ABSTRACT ObjectiveTo examine the association between chronic hypertension (CH) and a wide range of adverse pregnancy outcomes after adjustment for confounding factors in obstetric history and maternal characteristics. MethodsThis was a prospective screening study for adverse pregnancy outcomes in women with singleton pregnancy attending their first routine hospital visit at 11 + 0 to 13 + 6 weeks' gestation. Data on maternal characteristics, medical and obstetric history and pregnancy outcome were collected. Regression analysis was performed to examine the association between CH and adver...
Source: Ultrasound in Obstetrics and Gynecology - Category: Radiology Authors: Tags: Original Paper Source Type: research
Abstract OBJECTIVE: To examine the association between chronic hypertension (CH) and a wide range of adverse pregnancy outcomes after adjustment for confounding factors in obstetric history and maternal characteristics. METHODS: This was a prospective screening study for adverse pregnancy outcomes in women with singleton pregnancies attending the first routine hospital visit at 11(+0) -13(+6) weeks' gestation. Data on maternal characteristics, medical and obstetric history and pregnancy outcomes were collected. Regression analysis was performed to examine the association between CH and adverse pregnancy outco...
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
ABSTRACT ObjectiveTo examine the association between chronic hypertension (CH) and a wide range of adverse pregnancy outcomes after adjustment for confounding factors in obstetric history and maternal characteristics. MethodsThis was a prospective screening study for adverse pregnancy outcomes in women with singleton pregnancies attending the first routine hospital visit at 11+0‐13+6 weeks’ gestation. Data on maternal characteristics, medical and obstetric history and pregnancy outcomes were collected. Regression analysis was performed to examine the association between CH and adverse pregnancy outcomes including l...
Source: Ultrasound in Obstetrics and Gynecology - Category: Radiology Authors: Tags: Original Paper Source Type: research
ConclusionImplementation of a structured MOC for women with GDM helped achieve pregnancy outcomes similar to those without GDM.
Source: Journal of Obstetrics and Gynaecology Research - Category: OBGYN Authors: Tags: Original Article Source Type: research
OBJECTIVE Recent guidelines recommend testing at
Source: Diabetes Care - Category: Endocrinology Authors: Tags: Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research
Magzati és anyai betegségek kockázata 40 évesnél idősebb édesanyák esetén. Orv Hetil. 2015 Dec;156(49):1987-1990 Authors: Vanya M, Szili K, Devosa I, Bártfai G Abstract A rising trend in advanced maternal age has been observed over the last few decades. Several studies have assessed the association between advanced maternal age and adverse pregnancy outcome, including miscarriage, stillbirth, pre-eclampsia, gestational hypertension, gestational diabetes mellitus, preterm birth, delivery of a small- or large-for-gestational-age neonates an...
Source: Orvosi Hetilap - Category: Journals (General) Authors: Tags: Orv Hetil Source Type: research
Abstract AimThe aim of this study was to determine pregnancy outcomes among early adolescent women (aged ≤ 15 years) compared with those in late adolescence (16–19 years) and adults aged 20–30 years. Material and MethodsA retrospective cohort study was conducted on singleton pregnancies with maternal age ≤15 years (early adolescent), 16–19 years (late adolescent), and 20–30 years (adult). The primary outcomes for comparison were the rates of preterm birth, low birthweight, growth restriction and cesarean section. ResultsA total of 33 777 pregnancies, 298 earl...
Source: Journal of Obstetrics and Gynaecology Research - Category: OBGYN Authors: Tags: Original Article Source Type: research
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