Sex hormone binding globulin for prediction of gestational diabetes mellitus in pre-conception and pregnancy: A systematic review

Gestational diabetes mellitus (GDM) affects approximately 1-24% of pregnancies [1]. It is defined as glucose intolerance that is recognized for the first time during pregnancy [2]. GDM is associated with adverse complications for the mother (pre-eclampsia, cesarean section) and the fetus (dystocia, large for gestational age, and macrosomia) [3-5]. Early prediction of GDM can lead to appropriate interventions such as lifestyle changes or pharmacological means to reduce adverse health impact. There is no standard agreed-upon screening protocol for GDM.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Tags: Review Source Type: research