A novel Ca2+-signal transduction inhibitor, kujigamberol C, isolated from Kuji amber.

A novel Ca2+-signal transduction inhibitor, kujigamberol C, isolated from Kuji amber.
Biosci Biotechnol Biochem. 2019 May 02;:1-5
Authors: Takahashi H, Koshino H, Maruyama M, Shinden H, Kimura KI
Abstract
A novel labdane type diterpenoid, 15-nor-8-labden-13-ol, named kujigamberol C, was isolated from Kuji amber using a modified isolation method to increase the yield of biologically active compounds. The structure was determined using HREIMS, 1D and 2D NMR. Kujigamberol C showed growth-restoring activity against mutant yeast via Ca2+-signal transduction.
PMID: 31045479 [PubMed - as supplied by publisher]

Source: Bioscience, Biotechnology, and Biochemistry - May 1, 2019 Category: Biochemistry Authors: Takahashi H, Koshino H, Maruyama M, Shinden H, Kimura KI Tags: Biosci Biotechnol Biochem Source Type: research