DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer

Genetic aberrations in DNA repair genes are linked to cancer, but less is reported about epigenetic regulation of DNA repair and functional consequences. We investigated the intragenic methylation loss at the ...

Source: Clinical Epigenetics - May 3, 2019 Category: Research Authors: Christoph Weigel, Jittiporn Chaisaingmongkol, Yassen Assenov, Christine Kuhmann, Volker Winkler, Irene Santi, Olga Bogatyrova, Simone Kaucher, Justo L. Bermejo, Suet Y. Leung, Tsun L. Chan, Felix Lasitschka, Manfred H. Bohrer, Alexander Marx, Roland Heyny Tags: Research Source Type: research