Combined Modality Therapy for Management of Esophageal Cancer: Current Approach Based on Experiences from East and West.

Combined Modality Therapy for Management of Esophageal Cancer: Current Approach Based on Experiences from East and West.
Surg Clin North Am. 2019 Jun;99(3):479-499
Authors: Moaven O, Wang TN
Abstract
Human evolutionary genetic divergence and distinctive environmental exposures have contributed to the development of clinicopathologic variations of esophageal cancer in Eastern and Western countries. Different treatment strategies have derived from the disparate regional experiences. Treatment strategy is more standardized in the West. Trimodality treatment with neoadjuvant chemoradiation followed by surgery is widely accepted as the standard treatment of locally advanced esophageal adenocarcinoma and esophageal squamous cell carcinoma. Trimodality treatment has not been adopted in many Eastern countries, and standard treatment is neoadjuvant chemotherapy. Several randomized trials are ongoing that may alter the standard management of esophageal cancer worldwide.
PMID: 31047037 [PubMed - in process]

Source: The Surgical Clinics of North America - May 4, 2019 Category: Surgery Authors: Moaven O, Wang TN Tags: Surg Clin North Am Source Type: research